Recombinant Viral B18R Protein

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Recombinant Viral B18R Protein

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Cat.No. : B18R-174
Product Overview : Recombinant viral B18R (His20-Glu351) protein with Fc region of human Human IgG1 (Pro100-Lys300) at N-terminus was expressed in Human embryonic kidney cell, HEK293.
Description : Counteracts the antiviral effects of host IFN-alpha/beta. Acts as a soluble IFN-alpha receptor and thus inhibits the interaction between host IFN-alpha and its receptor.
Source : HEK293
Species : Viral
Form : Disulfide-linked homodimer
Bio-activity : Measured by its ability to inhibit Type-I IFN-mediated anti-viral activity. The ED50 for this effect, as measured by inhibition of recombinant Human IFN‑ alpha 2, is 0.3-1.8 ng/mL.
Molecular Mass : 65 kDa
N-terminal Sequence Analysis : Met-Asp-Pr o100
Endotoxin : <0.10 EU per 1 μg of the protein by the LAL method.
Purity : >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Storage Buffer : Lyophilized from a 0.2 μm filtered solution in PBS.
Preservative : Reconstitute at 500 μg/mL in PBS.
Gene Name : B19R temporal expression: early [ Vaccinia virus ]
Official Symbol : B19R
Synonyms : IFN-alpha/beta-receptor-like secreted glycoprotein; similar to VACCP-B19R; host defense modulator [VACWR-B18R]; B18R; B19R
Gene ID : 3707577
UniProt ID : P25213

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