Recombinant Zaire Ebolavirus VP35 Protein (1-340 aa), His-Myc-tagged
| Cat.No. : | VP35-2295Z |
| Product Overview : | Recombinant Zaire Ebolavirus (strain Kikwit-95) (ZEBOV) (Zaire Ebola virus) VP35 Protein (1-340 aa) is produced by E. coli expression system. This protein is fused with a 10xHis tag at the N-terminal and a Myc tag at the C-terminal. Protein Description: Full Length. |
- Specification
- Gene Information
- Related Products
| Description : | Acts as a polymerase cofactor in the RNA polymerase transcription and replication complex. Prevents establishment of cellular antiviral state by blocking virus-induced phosphorylation and activation of interferon regulatory factor 3 (IRF3), a transcription factor critical for the induction of interferons alpha and beta. This blockage is produced through the interaction with and inhibition host IKBKE and TBK1 producing a strong inhibition of the phosphorylation and activation of IRF3. Also inhibits the antiviral effect mediated by the interferon-induced, double-stranded RNA-activated protein kinase EIF2AK2/PKR. |
| Source : | E. coli |
| Species : | Zaire Ebolavirus |
| Tag : | His-Myc |
| Form : | Tris-based buffer,50% glycerol |
| Molecular Mass : | 42.4 kDa |
| Protein length : | 1-340 aa |
| AA Sequence : | MTTRTKGRGHTAATTQNDRMPGPEL SGWISEQLMTGRIPVSDIFCDIENN PGLCYASQMQQTKPNPKTRNSQTQT DPICNHSFEEVVQTLASLATVVQQQ TIASESLEQRITSLENGLKPVYDMA KTISSLNRVCAEMVAKYDLLVMTTG RATATAAATEAYWAEHGQPPPGPSL YEESAIRGKIESRDETVPQSVREAF NNLDSTTSLTEENFGKPDISAKDLR NIMYDHLPGFGTAFHQLVQVICKLG KDSNSLDIIHAEFQASLAEGDSPQC ALIQITKRVPIFQDAAPPVIHIRSR GDIPRACQKSLRPVPPSPKIDRGWV CVFQLQDGKTLGLKI |
| Purity : | > 85% as determined by SDS-PAGE. |
| Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
| Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
| Concentration : | A hardcopy of COA will be sent along with the products. Please refer to it for detailed information. |
| Gene Name : | VP35 polymerase complex protein [ Zaire ebolavirus ] |
| Official Symbol : | VP35 |
| Synonyms : | VP35; |
| Gene ID : | 911827 |
| UniProt ID : | Q6V1Q9 |
Products Types
| ◆ Recombinant Protein | ||
| VP35-5112Z | Recombinant Zaire Ebola virus VP35 protein, His&Myc-tagged | +Inquiry |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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