Recombinant Zebrafish ABCG4B

• Cat.No.: ABCG4B-6256Z
• Product Overview: Recombinant Zebrafish ABCG4B full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Zebrafish
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 oC for short term. For long term storage, store it at -20 oC～-80 oC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: abcg4b ATP-binding cassette, sub-family G (WHITE), member 4b [ Danio rerio (zebrafish) ]
• Official Symbol: ABCG4B
• Gene ID: 794238
• mRNA Refseq: NM_001111212
• Protein Refseq: NP_001104682
• UniProt ID: A8KB77

Reviews

11/09/2021

The protein product dissolved effortlessly in the recommended solvent, allowing for easy and convenient preparation."

07/10/2020

The protein product I purchased demonstrated outstanding purity.

10/27/2018

Simple to dispense and store without any spills or mess.

07/13/2017

The protein product provide minimal contamination and excellent batch-to-batch consistency.

03/11/2017

I appreciated the protein product's user-friendly packaging

Q&As

Is ABCG4b found in the genus Danio?

Yes, ABCG4b is found in the genus Danio, which includes various species of fish known as danios.

Is ABCG4b present in vertebrates?

Yes, ABCG4b is present in vertebrates since it is part of the taxonomic lineage "Vertebrata."

What is the regulatory mechanism of ABCG4b expression?

The regulatory mechanisms controlling ABCG4b expression are not well-characterized. Transcriptional regulators, signaling pathways, and cellular cues may influence its expression levels. 

Does ABCG4b occur in ray-finned fishes?

Yes, ABCG4b occurs in ray-finned fishes as it is part of the taxonomic lineage "Actinopterygii."

Is ABCG4b primarily localized on the plasma membrane?

The subcellular localization of ABCG4b is not clearly defined. However, like other ABC transporters, it is expected to be primarily localized on the plasma membrane, where it can interact with extracellular and intracellular substrates.

Is ABCG4b found in eukaryotic organisms?

Yes, ABCG4b is found in eukaryotic organisms since it belongs to the taxonomic lineage "Eukaryota."

Does ABCG4b exist in metazoans?

Yes, ABCG4b exists in metazoans as it is part of the taxonomic lineage "Metazoa."

Are there any known physiological substrates of ABCG4b?

The specific physiological substrates of ABCG4b are currently unknown. ABC transporters typically have diverse substrate specificities, including lipids, sterols, and xenobiotic compounds.

Is ABCG4b present in other members of the family Danionidae?

Yes, ABCG4b is present in other members of the family Danionidae since it is part of the taxonomic lineage "Danionidae."

Is ABCG4b associated with drug resistance in cancer?

There is limited information available regarding the association of ABCG4b with drug resistance in cancer. The involvement of ABC transporters, including ABCG4, in drug resistance has been observed in various studies.

What is the specific molecular function of ABCG4b?

According to the GO annotations, the molecular function of ABCG4b is ATP binding. It likely binds to ATP molecules to facilitate its transport function.

Does ABCG4b have ATPase activity?

The GO annotations do not explicitly mention ATPase activity for ABCG4b. However, being an ATP-binding cassette (ABC) transporter, it is possible that ABCG4b has ATPase activity, as ATP hydrolysis is typically associated with ABC transporters' transport function.

re there any known genetic variants or mutations of ABCG4b associated with diseases?

Currently, there is limited information regarding genetic variants or mutations specifically associated with ABCG4b and diseases. It is possible that genetic variations or mutations in ABCG4b could influence its function or expression, potentially affecting disease susceptibility. 

Does ABCG4b play a role in lipid metabolism?

The role of ABCG4b in lipid metabolism is not well-established. However, considering its similarity to other ABC transporters involved in lipid transport, it is plausible that ABCG4b may have a role in lipid metabolism.

What is the function of ABCG4b in cellular processes?

The specific function of ABCG4b is not well-documented. However, as a member of the ABC transporter family, it is likely involved in the transport of various substrates across cellular membranes.