Recombinant Zebrafish ACTC1B

• Cat.No.: ACTC1B-9132Z
• Product Overview: Recombinant Zebrafish ACTC1B full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Zebrafish
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 oC for short term. For long term storage, store it at -20 oC～-80 oC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: actc1b actin, alpha, cardiac muscle 1b [ Danio rerio (zebrafish) ]
• Official Symbol: ACTC1B
• Gene ID: 58114
• mRNA Refseq: NM_131591
• Protein Refseq: NP_571666
• UniProt ID: Q9I8V1

Reviews

03/05/2022

The product's consistent performance allows for accurate and reliable data analysis.

05/06/2021

The customer support team demonstrates deep knowledge and expertise, providing valuable guidance and troubleshooting assistance.

06/12/2017

The protein consistently demonstrates superior performance compared to other similar products on the market.

02/09/2017

The product undergoes rigorous quality control measures, meeting the highest industry standards.

01/25/2016

The packaging was well-designed, protecting the protein from any potential damage during transportation.

Q&As

Does the actc1b mutation lead to more severe muscle defects or does it result in a milder phenotype?

The actc1b mutation in zebrafish leads to mild muscle defects.

How does the compensatory transcriptional upregulation of an actin paralogue relate to the actc1b mutation?

The compensatory transcriptional upregulation of an actin paralogue is a response to the actc1b mutation, potentially mitigating the impact of the mutation.

How does the actc1b mutant respond to injection of the actc1b targeting morpholino?

The actc1b mutant is unaffected by the injection of the actc1b targeting morpholino.

Does actc1b targeting morpholino injection rescue or exacerbate the muscle defects in the actc1b mutant?

The impact of actc1b targeting morpholino injection on the actc1b mutant phenotype has not been specified.The effect of actc1b targeting morpholino injection on the muscle defects in the actc1b mutant has not been described in the provided details.

Can the compensatory transcriptional upregulation of the actin paralogue serve as a potential therapeutic strategy for actin myopathy?

The compensatory transcriptional upregulation of the actin paralogue may serve as a potential therapeutic strategy for actin myopathy.

What is the impact of actc1b targeting morpholino injection on the actc1b mutant phenotype?

The actc1b mutation results in a milder phenotype rather than more severe muscle defects.

What contributes to the milder phenotype observed in the actc1b mutant?

The milder phenotype is attributed to a compensatory transcriptional upregulation of an actin paralogue.

Is the compensatory transcriptional upregulation observed specifically in response to the actc1b mutation?

Yes, the compensatory transcriptional upregulation of the actin paralogue is observed specifically in response to the actc1b mutation.

What is the role of ACTc1b in normal muscle function?

ACTc1b plays a critical role in muscle contraction and provides structural support to muscle fibers.

What is the observed effect of the actc1b mutant on muscle function?

The actc1b mutant exhibits mild muscle defects.

How does the actc1b mutation affect muscle defects in zebrafish?

ACTc1b is primarily involved in muscle contraction and provides structural support to muscle fibers.

Does the compensatory upregulation of the actin paralogue alleviate the muscle defects associated with actin myopathy?

The compensatory upregulation of the actin paralogue may alleviate the muscle defects associated with actin myopathy, offering a novel approach for the treatment of the condition.