cd3g
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  • Official Full Name
  • CD3g molecule, gamma (CD3-TCR complex)
  • Background
  • The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency.
  • Synonyms
  • CD3G; CD3g molecule, gamma (CD3-TCR complex); CD3g antigen, gamma polypeptide (TiT3 complex); T-cell surface glycoprotein CD3 gamma chain; T-cell receptor T3 gamma chain; CD3g molecule, epsilon (CD3-TCR complex); T-cell antigen receptor complex, gamma sub
Cat.#:Cd3g-323MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse CD3G Protein, Fc-tagged
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Cat.#:Cd3g-324MTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse CD3G Protein
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Cat.#:CD3G-0805HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CD3G Protein, GST-Tagged
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Cat.#:CD3E & CD3G-251HTag:His/Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD3E & CD3G protein, His/Fc-tagged
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Cat.#:CD3E & CD3G-342HTag:His & Fc & Flag
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD3E & CD3G protein, His & Fc & Flag-tagged
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Cat.#:CD3G-26368THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human CD3G
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Cat.#:CD3G-370HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human CD3G
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Cat.#:CD3G-4903HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD3G protein, Fc-tagged
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Cat.#:CD3G-7556HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CD3G, His-tagged
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Cat.#:CD3G-3088MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CD3G Protein
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Cat.#:CD3G-1251RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CD3G Protein
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Cat.#:CD3G-391CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus CD3G Protein, His-tagged
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Cat.#:CD3G-738RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CD3G Protein, His-tagged
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Cat.#:CD3E & CD3G-761HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD3E & CD3G cell lysate
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Cat.#:CD3G-7675HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CD3G 293 Cell Lysate
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Involved Pathway

CD3G involved in several pathways and played different roles in them. We selected most pathways CD3G participated on our site, such as Hematopoietic cell lineage, T cell receptor signaling pathway, Chagas disease (American trypanosomiasis), which may be useful for your reference. Also, other proteins which involved in the same pathway with CD3G were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Hematopoietic cell lineage
CD3E; CD3D; KIT; IL7; CD4; ITGA5; IL3RA; IL2RA; GP1BB; FCGR1A; IL9R
T cell receptor signaling pathway
NFATC1; CARD11; CD3E; IKBKB; MAP2K1; PAK1; SHB; NCK2; NFATC3; PIK3R3
Chagas disease (American trypanosomiasis)
NOS2; CD247; Il2; PPP2CB; MAP2K4; PIK3CB; TLR2; C3; CCL2; TNFRSF1A
Measles
TRAF6; STAT1; IL12B; Cd209g; TNFRSF10A; IFNA6; Ifna11; IFNA8; IFNA4; PIK3CB
HTLV-I infection
WNT5A; IL6; H2-AB1; NFYB; VCAM1; WNT10B; PPP3CB; POLD1; FZD8; FDPS

Protein Function

CD3G has several biochemical functions, for example, T cell receptor binding, protein heterodimerization activity, receptor signaling complex scaffold activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CD3G itself. We selected most functions CD3G had, and list some proteins which have the same functions with CD3G. You can find most of the proteins on our site.
Function
Related Protein
Function T cell receptor binding
Related Protein CD3E; HLA-A; CD3G; FYN; H2-Q10; DOCK2; EPS8L1; CD1d1
Function protein heterodimerization activity
Related Protein AGTR1; H2AFVB; RRAGC; HIST1H4B; HIST1H2BH; ITGA3; EGFR; HIST2H2L; HIST1H2BA; SFRP5
Function receptor signaling complex scaffold activity
Related Protein G3BP2; SHANK1; GRIP2A; RGS14; CARD10; AXIN1; LRRK2; GRIP1; SPAG9; NCK1
Function transmembrane signaling receptor activity
Related Protein ERBB3; BAI2; TLR1; NFAM1; GLP1R; OR115-6; P2RX5; TRPV1; CALCRLA; TLR2

Interacting Protein

CD3G has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD3G here. Most of them are supplied by our site. Hope this information will be useful for your research of CD3G.
CD3E