csf1r
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  • Official Full Name
  • colony stimulating factor 1 receptor
  • Background
  • Macrophage-colony stimulating factor (M-CSF, CSF-1) receptor is an integral membrane tyrosine kinase encoded by the c-fms proto-oncogene. M-CSF receptor is expressed in monocytes (macrophages and their progenitors) and drives growth and development of thi
  • Synonyms
  • CSF1R; colony stimulating factor 1 receptor; macrophage colony-stimulating factor 1 receptor; c-fms; CSF-1-R; CSF-1 receptor; proto-oncogene fms; proto-oncogene c-Fms; Fms; CD115; Csfmr; Fim-2; CSF-1R; M-CSFR; M-CSF-R; AI323359; CSFR; FIM2; HDLS
Cat.#:CSF1R-1970HTag:His-GST
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human CSF1R protein (aa 543-922), His-GST-tagged
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Cat.#:CSF1R-001HTag:HIgG/His
Source (Host):Insect cellSpecies:Human
Product nameRecombinant Human CSF1R Protein, hIgG-His-tagged
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Cat.#:CSF1R-022HTag:His-Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human CSF1R Protein, His-Avi-tagged, Biotinylated
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Cat.#:CSF1R-352HTag:MIgG2a Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human CSF1R Protein (Met1-Pro517), MIgG2a Fc-tagged
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Cat.#:Csf1r-4001MTag:His-Avi
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Csf1r Protein, His-Avi-tagged, Biotinylated
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Cat.#:CSF1R-429CTag:His-SUMO
Source (Host):E. coliSpecies:Cat
Product nameRecombinant Cat CSF1R Protein (20-514 aa), His-SUMO-tagged
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Cat.#:CSF1R-979RTag:HlgG1 Fc
Source (Host):HEK293Species:Rhesus
Product nameRecombinant Rhesus CSF1R Protein (Met1-Glu512) (Cys378Arg), HlgG1 Fc-tagged
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Cat.#:CSF1R-980RTag:His
Source (Host):HEK293Species:Rhesus
Product nameRecombinant Rhesus CSF1R Protein (Met1-Glu512) (Cys378Arg), His-tagged
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Cat.#:CSF1R-1964HTag:GST
Source (Host):Insect CellsSpecies:Human
Product nameRecombinant Human CSF1R Protein, GST-tagged
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Cat.#:CSF1R-1965HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CSF1R Protein, GST-tagged
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Cat.#:Csf1r-1966MTag:GST
Source (Host):Wheat GermSpecies:Mouse
Product nameRecombinant Mouse Csf1r Protein, GST-tagged
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Cat.#:CSF1R-1666HTag:N/A
Source (Host):NS0Species:Human
Product nameRecombinant Human Colony Stimulating Factor 1 Receptor
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Cat.#:CSF1R-320HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human CSF1R, GST-tagged, Active
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Cat.#:CSF1R-021HTag:His
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human CSF1R Protein, His-tagged
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Cat.#:CSF1R-192HTag:His/GST
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human CSF1R Protein, His & GST-tagged
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Cat.#:CSF1R-28792THTag:
Source (Host):Species:Human
Product nameRecombinant Human CSF1R
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Cat.#:CSF1R-39HTag:FC/His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CSF1R, Fc-His tagged
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Cat.#:CSF1R-469HTag:Fc Chimera
Source (Host):NSO cellsSpecies:Human
Product nameRecombinant Human CSF1R, Fc Chimera
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Cat.#:CSF1R-470HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human CSF1R protein, Fc-tagged
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Cat.#:CSF1R-49HTag:Flag
Source (Host):Insect cellSpecies:Human
Product nameRecombinant Human CSF1R protein, Flag-tagged, Biotinylated
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Cat.#:CSF1R-58HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human CSF1R protein, MYC/DDK-tagged
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Cat.#:CSF1R-7031HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CSF1R protein, His-tagged
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Cat.#:CSF1R-804HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human CSF1R, None tagged
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Cat.#:CSF1R-805HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CSF1R, His tagged
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Cat.#:CSF1R-935HTag:DDK/His
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human CSF1R Protein, DDK/His-tagged
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Cat.#:CSF1R-936HTag:DDK
Source (Host):Sf9 cellsSpecies:Human
Product nameRecombinant Human CSF1R Protein, DDK-tagged
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Cat.#:Csf1r-337MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Csf1r protein, His-tagged
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Cat.#:Csf1r-4000MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Csf1r, His tagged
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Cat.#:Csf1r-7032MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Csf1r protein, His-tagged
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Cat.#:Csf1r-8665MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Csf1r Protein, Fc-tagged
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Cat.#:Csf1r-8666MTag:FC/His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Csf1r, Fc-His tagged
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Cat.#:Csf1r-54RTag:His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Csf1r, Fc tagged
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Cat.#:Csf1r-55RTag:FC/His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Csf1r, His tagged
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Cat.#:Csf1r-7033RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Csf1r protein, His-tagged
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Cat.#:CSF1R-346CTag:Fc
Source (Host):HEK293Species:Cynomolgus
Product nameRecombinant Cynomolgus CSF1R protein, Fc-tagged
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Cat.#:CSF1R-65CTag:His
Source (Host):HEK293Species:Cynomolgus
Product nameRecombinant Cynomolgus CSF1R Protein, His-tagged
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Cat.#:CSF1R-2739HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CSF1R cell lysate
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Cat.#:CSF1R-444HCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human CSF1R cell lysate
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Cat.#:CSF1R-2091MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse CSF1R cell lysate
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Cat.#:CSF1R-823RCLTag:
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat CSF1R cell lysate
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Cat.#:Kit-1574Tag:
Source (Host):Species:
Product nameCSF1R Kinase Binding Assay Kit
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Involved Pathway

CSF1R involved in several pathways and played different roles in them. We selected most pathways CSF1R participated on our site, such as C-MYB transcription factor network, Cytokine-cytokine receptor interaction, Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with CSF1R were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
C-MYB transcription factor network
ELANE; LECT2; SMARCA2; CREBBP; ADA; PIAS3; SKI; MYF6; TRIM28; COL1A2
Cytokine-cytokine receptor interaction
Pdgfa&Pdgfb; TNFRSF17; IL8L1; ACVR1B; PRLR; Il6ra; PRLRA; IFNA10; IFNA21; IL3RA
Endocytosis
SPG20; VPS4B; ASAP2; ERBB3B; GRK5; RAB5B; CHMP2BA; SNX6; RHOAD; MHC1UEA
Hematopoietic cell lineage
CD1A; EPO; IL1B; GYPA; ITGA2; CD4; CD1E; IL4R; ITGA6; CD19
Integrins in angiogenesis
ANGPTL3; EDIL3; CSF1; MFGE8; CSF1R
Osteoclast differentiation
LILRA2; NFATC2; SIRPA; ITGB3; PIK3CG; TNFSF11; IFNGR2; FCGR4; LILRA5; TREM2
PI3K-Akt signaling pathway
CSH2; PRP2; CDC37; CSF1R; LAMC3; CSF3; LOC608458; CSH1; EFNA2; CHAD
Pathways in cancer
Fzd4; NOS2; ARAF; ERBB2; FGF13; FGF9; CBLC; EP300; MAPK3; CCNE2

Protein Function

CSF1R has several biochemical functions, for example, ATP binding, cytokine binding, macrophage colony-stimulating factor receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CSF1R itself. We selected most functions CSF1R had, and list some proteins which have the same functions with CSF1R. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein GATC; STK17A; LARS2; SNRNP200; PKDCCA; ATP2B1; DDX39AA; UBE2D2; CPS1; ERCC6L
Function cytokine binding
Related Protein CRLF1; Fzd4; CSF1RA; IL17F; CXCR4; CNTFR; CHRD; IL31RA; NRP2; LIFR
Function macrophage colony-stimulating factor receptor activity
Related Protein CSF1R; MST1R
Function protein homodimerization activity
Related Protein B4GALT1; TOX3; TGFB2; SLC26A5; MZF1; SUPV3L1; RAB11FIP4A; CEBPA; CARM1; PAH
Function protein phosphatase binding
Related Protein CDH5; JUPA; DRD1A; FGF19; VCAN; IRS2; MVP; GRB2; JAK3; DLG3

Interacting Protein

CSF1R has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CSF1R here. Most of them are supplied by our site. Hope this information will be useful for your research of CSF1R.
Plcg2; saicar; PKM; GRAP2; HSP90AB1; PIK3R1; yqeH; hppD; purL; Src; FYN; Fyn; Yes1

CSF1R Related Articles

Shi, M; Movius, J; et al. Cerebrospinal Fluid Peptides as Potential Parkinson Disease Biomarkers: A Staged Pipeline for Discovery and Validation. MOLECULAR & CELLULAR PROTEOMICS 14:544-555(2015).
Moffat, L; Rothwell, L; et al. Development and characterisation of monoclonal antibodies reactive with porcine CSF1R (CD115). DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 47:123-128(2014).