Recombinant Human CSF1R Protein (Ile20-Leu514), C-6×His-tagged
Cat.No. : | CSF1R-076H |
Product Overview : | Recombinant Human CSF1R Protein (Ile20-Leu514) with C-6×His tag was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL), HL cell lines and anaplastic large cell lymphoma. |
Source : | HEK293 |
Species : | Human |
Tag : | C-6×His |
Form : | Lyophilized |
Molecular Mass : | 55.6 kDa |
Protein Length : | Ile20-Leu514 |
Purity : | > 95% as determined by SDS-PAGE and Coomassie blue staining. |
Storage : | Store at -80 centigrade for 12 months (Avoid repeated freezing and thawing) |
Storage Buffer : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 54 % trehalose is added as protectants before lyophilization. |
Reconstitution : | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. |
Gene Name : | CSF1R colony stimulating factor 1 receptor [ Homo sapiens (human) ] |
Official Symbol : | CSF1R |
Synonyms : | CSF1R; colony stimulating factor 1 receptor; FMS, McDonough feline sarcoma viral (v fms) oncogene homolog; macrophage colony-stimulating factor 1 receptor; C FMS; CD115; CSFR; CSF-1-R; CD115 antigen; CSF-1 receptor; FMS proto-oncogene; proto-oncogene c-Fms; macrophage colony stimulating factor I receptor; McDonough feline sarcoma viral (v-fms) oncogene homolog; FMS; FIM2; HDLS; C-FMS; CSF-1R; M-CSF-R; |
Gene ID : | 1436 |
mRNA Refseq : | NM_005211 |
Protein Refseq : | NP_005202 |
MIM : | 164770 |
UniProt ID : | P07333 |
Products Types
◆ Recombinant Protein | ||
CSF1R-1965H | Recombinant Human CSF1R Protein, GST-tagged | +Inquiry |
CSF1R-180H | Recombinant Human CSF1R Protein, His (Fc)-Avi-tagged | +Inquiry |
CSF1R-352H | Active Recombinant Human CSF1R protein(Met1-Pro517), mFc-tagged | +Inquiry |
CSF1R-020H | Recombinant Human CSF1R Protein, C-His-tagged | +Inquiry |
Csf1r-2339M | Recombinant Mouse Csf1r Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
CSF1R-2739HCL | Recombinant Human CSF1R cell lysate | +Inquiry |
CSF1R-444HCL | Recombinant Human CSF1R cell lysate | +Inquiry |
CSF1R-823RCL | Recombinant Rat CSF1R cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1574 | CSF1R Kinase Binding Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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