Recombinant Mouse Csf1r Protein, Fc-tagged
Cat.No. : | Csf1r-376M |
Product Overview : | Recombinant Mouse Csf1r protein with Fc tag was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
- Download
Description : | Enables several functions, including macrophage colony-stimulating factor receptor activity; protein homodimerization activity; and protein phosphatase binding activity. Involved in several processes, including nervous system development; positive regulation of protein phosphorylation; and protein phosphorylation. Located in cell surface and plasma membrane. Part of CSF1-CSF1R complex. Is expressed in several structures, including alimentary system; central nervous system; extraembryonic component; genitourinary system; and limb. Human ortholog(s) of this gene implicated in adult-onset leukoencephalopathy with axonal spheroids and pigmented glia and renal cell carcinoma. Orthologous to human CSF1R (colony stimulating factor 1 receptor). |
Source : | HEK293 |
Species : | Mouse |
Tag : | Fc |
Form : | Lyophilized |
Molecular Mass : | 81.8 kDa |
Protein length : | 977 |
AA Sequence : | MELGPPLVLLLATVWHGQGAPVIEP SGPELVVEPGETVTLRCVSNGSVEW DGPISPYWTLDPESPGSTLTTRNAT FKNTGTYRCTELEDPMAGSTTIHLY VKDPAHSWNLLAQEVTVVEGQEAVL PCLITDPALKDSVSLMREGGRQVLR KTVYFFSPWRGFIIRKAKVLDSNTY VCKTMVNGRESTSTGIWLKVNRVHP EPPQIKLEPSKLVRIRGEAAQIVCS ATNAEVGFNVILKRGDTKLEIPLNS DFQDNYYKKVRALSLNAVDFQDAGI YSCVASNDVGTRTATMNFQVVESAY LNLTSEQSLLQEVSVGDSLILTVHA DAYPSIQHYNWTYLGPFFEDQRKLE FITQRAIYRYTFKLFLNRVKASEAG QYFLMAQNKAGWNNLTFELTLRYPP EVSVTWMPVNGSDVLFCDVSGYPQP SVTWMECRGHTDRCDEAQALQVWND THPEVLSQKPFDKVIIQSQLPIGTL KHNMTYFCKTHNSVGNSSQYFRAVS LGQSKQLPDESLFTPVVVACMSVMS LLVLLLLLLLYKYKQKPKYQVRWKI IERYEGNSYTFIDPTQLPYNEKWEF PRNNLQFGKTLGAGAFGKVVEATAF GLGKEDAVLKVAVKMLKSTAHADEK EALMSELKIMSHLGQHENIVNLLGA CTHGGPVLVITEYCCYGDLLNFLRR KAEAMLGPSLSPGQDSEGDSSYKNI HLEKKYVRRDSGFSSQGVDTYVEMR PVSTSSSDSFFKQDLDKEASRPLEL WDLLHFSSQVAQGMAFLASKNCIHR DVAARNVLLTSGHVAKIGDFGLARD IMNDSNYVVKGNARLPVKWMAPESI FDCVYTVQSDVWSYGILLWEIFSLG LNPYPGILVNNKFYKLVKDGYQMAQ PVFAPKNIYSIMQSCWDLEPTRRPT FQQICFLLQEQARLERRDQDYANLP SSGGSSGSDSGGGSSGGSSSEPEEE SSSEHLACCEPGDIAQPLLQPNNYQ FC |
Purity : | > 98% |
Applications : | WB; ELISA; FACS; FC |
Stability : | This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
Storage : | At -20 centigrade. |
Concentration : | 1 mg/mL |
Storage Buffer : | PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
Reconstitution : | Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
Gene Name : | Csf1r colony stimulating factor 1 receptor [ Mus musculus (house mouse) ] |
Official Symbol : | Csf1r |
Synonyms : | Csf1r; colony stimulating factor 1 receptor; Fms; Fim2; CD115; Csfmr; Fim-2; CSF-1R; M-CSFR; M-CSF-R; macrophage colony-stimulating factor 1 receptor; Names; CSF-1 receptor; CSF-1-R; c-fms; proto-oncogene c-Fms; proto-oncogene fms; EC 2.7.10.1 |
Gene ID : | 12978 |
mRNA Refseq : | NM_001037859 |
Protein Refseq : | NP_001032948 |
UniProt ID : | P09581 |
Products Types
◆ Lysates | ||
CSF1R-823RCL | Recombinant Rat CSF1R cell lysate | +Inquiry |
CSF1R-444HCL | Recombinant Human CSF1R cell lysate | +Inquiry |
CSF1R-2739HCL | Recombinant Human CSF1R cell lysate | +Inquiry |
Related Gene
Not For Human Consumption!
Inquiry
- Reviews
- Q&As
Customer Reviews (3)
Write a reviewWith its remarkable quality, reliability, and the manufacturer's excellent technical support, I am confident that it will be an invaluable asset in driving my scientific inquiries forward and facilitating groundbreaking discoveries in my field.
This variety allows me to select the most appropriate option based on the specific requirements of my research.
the manufacturer's commitment to quality control and rigorous testing guarantees the reliability and reproducibility of the CSF1R protein, which is essential for obtaining accurate and consistent results.
Q&As (5)
Ask a questionYes, drugs like pexidartinib have been approved for the treatment of certain rare tumors called tenosynovial giant cell tumors (TGCT) that overexpress CSF1R.
CSF1R inhibitors can modulate the tumor microenvironment by reducing the number of tumor-associated macrophages and promoting an anti-tumor immune response.
Yes, CSF1R inhibitors are often used in combination with chemotherapy and immunotherapy to enhance treatment effectiveness.
CSF1R inhibitors are being investigated for cancer therapy to block tumor-promoting macrophages and slow down cancer progression.
Research is ongoing, and CSF1R inhibitors are being explored as a potential therapy for neurodegenerative diseases, but no FDA-approved treatments currently exist.
Ask a Question for All Csf1r Products
Required fields are marked with *
My Review for All Csf1r Products
Required fields are marked with *
Inquiry Basket