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Official Full Name chemokine (C-X-C motif) ligand 16
Background Chemokine (C-X-C motif) ligand 16 (CXCL16), also known as SR-PSOX, is a transmembrane protein that facilitates uptake of low density lipoproteins by macrophages, resulting in foam cell formation. CXCL16 is found in liver tissue2 and influences the uptake, subcellular localization, and cytokine profile induced by D oligonucleotides. 3 CXCL16 may play a pro- inflammatory role in Inflammatory Bowel Disease (IBD), particularly Crohns disease.
Synonyms chemokine (C-X-C motif) ligand 16; SRPSOX; CXCLG16; SR-PSOX; CXCL16; CXC chemokine ligand 16; Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein; Small-inducible cytokine B16; Transmembrane chemokine CXCL16
    • Species :
    • Canine
    • Cynomolgus
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian Cell
    • NS0
    • Wheat Germ
    • Yeast
    • Tag :
    • Fc
    • GST
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CXCL16-1108H Recombinant Human CXCL16 Protein (Met1-Thr224), His-tagged HEK293 His
    Mouse Cxcl16-347M Recombinant Mouse Cxcl16 Protein, His-tagged Yeast His
    Human CXCL16-11721H Recombinant Human CXCL16, GST-tagged E.coli GST
    Human CXCL16-2164H Recombinant Human CXCL16 Protein, GST-tagged Wheat Germ GST
    Human CXCL16-330H Recombinant Human CXCL16, His-tagged NS0 His
    Human CXCL16-372H Recombinant Human Chemokine (C-X-C motif) Ligand 16 E.coli N/A
    Human CXCL16-7648H Recombinant Human CXCL16 protein, His & T7-tagged E.coli His/T7
    Human CXCL16-82H Recombinant Human Chemokine (C-X-C motif) Ligand 16 E.coli N/A
    Mouse Cxcl16-153M Recombinant Mouse Cxcl16, His tagged Human Cell His
    Mouse CXCL16-2545MCL Recombinant Mouse CXCL16 cell lysate Human Cell N/A
    Mouse Cxcl16-484M Recombinant Mouse Chemokine (C-X-C motif) Ligand 16, His-tagged NS0 His
    Mouse Cxcl16-7649M Recombinant Mouse Cxcl16 protein, His & T7-tagged E.coli His/T7
    Mouse Cxcl16-85M Recombinant Mouse Cxcl16 protein E.coli N/A
    Rat CXCL16-1083R Recombinant Rat CXCL16 Protein, His-tagged HEK293 His
    Rat CXCL16-1414RCL Recombinant Rat CXCL16 cell lysate Human Cell N/A
    Rat CXCL16-1688R Recombinant Rat CXCL16 Protein Mammalian Cell His
    Rat Cxcl16-7441R Recombinant Rat Cxcl16, Fc tagged Human Cell Fc
    Rat Cxcl16-7650R Recombinant Rat Cxcl16 protein, His & T7-tagged E.coli His/T7
    Cynomolgus CXCL16-253C Recombinant Cynomolgus CXCL16 Protein E.coli N/A
    Canine CXCL16-178C Recombinant Canine CXCL16, Fc tagged Human Cell Fc
    Canine CXCL16-259C Recombinant Canine CXCL16, His tagged Human Cell Fc
    Canine CXCL16-842CCL Recombinant Canine CXCL16 cell lysate Human Cell N/A

    CXCL16 involved in several pathways and played different roles in them. We selected most pathways CXCL16 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with CXCL16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction BMPR2; KITB; TGFB1; TNFRSF13B; IL18RAP; LEPA; LTB; EDAR; IFNA13; CXCL10
    Chemokine signaling pathway CXCR6; CCL28; VAV2; GNGT1; CCL1; PLCB1; XCR1; PIK3CD; CCL19; PRKACB

    CXCL16 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by CXCL16 itself. We selected most functions CXCL16 had, and list some proteins which have the same functions with CXCL16. You can find most of the proteins on our site.

    Function Related Protein
    chemokine activity IL-8; CXCL9; CCL22; CXL34B.11; XCL2; CCL25B; CCL19B; CXCL8B.3; CCL3L1; CCL35.1
    low-density lipoprotein receptor activity LRP6; LRP12; OLR1; LDLR; VLDLR; CXCL16
    scavenger receptor activity LGALS3BP; ENPP1; SCARA5; LGALS3BPB; ENPP2; CXCL16; LOXL3; SRCRB4D; MARCO; POLR1B

    CXCL16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CXCL16 here. Most of them are supplied by our site. Hope this information will be useful for your research of CXCL16.

    Wehr, A; Baeck, C; et al. Pharmacological Inhibition of the Chemokine CXCL16 Diminishes Liver Macrophage Infiltration and Steatohepatitis in Chronic Hepatic Injury. PLOS ONE 9:-(2014).
    Wang, L; Sun, SZ; et al. oxLDL-Induced Lipid Accumulation in Glomerular Podocytes: Role of IFN-gamma, CXCL16, and ADAM10. CELL BIOCHEMISTRY AND BIOPHYSICS 70:529-538(2014).

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