epo
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  • Official Full Name
  • erythropoietin
  • Background
  • This gene is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. [provided by RefSeq, Jul 2008]
  • Synonyms
  • EPO; erythropoietin; EP; MVCD2; epoetin;
Cat.#:EPO-355HTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human EPO Protein
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Cat.#:EPO-3423HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human EPO Protein, GST-tagged
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Cat.#:Epo-1847MTag:
Source (Host):CHO cellsSpecies:Mouse
Product nameRecombinant Mouse Epo Protein
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Cat.#:Epo-4376MTag:
Source (Host):YeastSpecies:Mouse
Product nameRecombinant Mouse Epo Protein
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Cat.#:Epo-1848RTag:
Source (Host):CHO cellsSpecies:Rat
Product nameRecombinant Rat Epo Protein
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Cat.#:EPO-4368BTag:
Source (Host):YeastSpecies:Bovine
Product nameRecombinant Bovine EPO Protein
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Cat.#:EPO-1203PTag:His
Source (Host):YeastSpecies:Pig
Product nameRecombinant Pig EPO Protein, His-tagged
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Cat.#:EPO-001HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human EPO, MIgG2a Fc-tagged
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Cat.#:EPO-002HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human EPO, HIgG1 Fc-tagged, mutant
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Cat.#:EPO-01HTag:N/A
Source (Host):CHOSpecies:Human
Product nameRecombinant Human Erythropoietin
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Cat.#:EPO-111HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human EPO, HIgG1 Fc-tagged
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Cat.#:EPO-163HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human Erythropoietin
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Cat.#:EPO-200HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human EPO Protein, Fc-tagged
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Cat.#:EPO-2291HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human EPO, His-tagged
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Cat.#:EPO-234HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human EPO, Fc-tagged
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Cat.#:EPO-252HTag:Strep II
Source (Host):HEK293Species:Human
Product nameRecombinant Human EPO, StrepII-tagged
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Cat.#:EPO-363HTag:His
Source (Host):Insect cellSpecies:Human
Product nameRecombinant Human EPO Protein, His-tagged
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Cat.#:EPO-451HTag:His
Source (Host):HEK293FSpecies:Human
Product nameRecombinant Human EPO protein, His-tagged
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Cat.#:EPO-513HTag:
Source (Host):CHOSpecies:Human
Product nameRecombinant Human EPO
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Cat.#:EPO-602HTag:His/GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human EPO protein, His & GST-tagged
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Cat.#:EPO-97HTag:N/A
Source (Host):CHOSpecies:Human
Product nameRecombinant Human erythropoietin, Fc-tagged
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Cat.#:EPOR-1614HTag:N/A
Source (Host):NS0Species:Human
Product nameRecombinant Human Erythropoietin Receptor
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Cat.#:Epo-603MTag:His/S
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Epo protein, His & S-tagged
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Cat.#:Epo-604MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Epo protein, His & T7-tagged
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Cat.#:Epo-7421MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Epo, His tagged
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Cat.#:Epo-966MTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Epo Protein
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Cat.#:EPO-2127RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat EPO Protein
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Cat.#:Epo-523RTag:His
Source (Host):HEK293FSpecies:Rat
Product nameRecombinant Rat Epo protein, His-tagged
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Cat.#:EPO-578RTag:Fc
Source (Host):Baculovirus-Insect CellsSpecies:Rat
Product nameRecombinant Rat EPO, Fc tagged
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Cat.#:Epo-606RTag:His/T7
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Epo protein, His & T7-tagged
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Cat.#:EPO-1196CTag:His
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus EPO Protein, His-tagged
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Cat.#:EPO-1487RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey EPO Protein, His-tagged
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Cat.#:Epo-104CTag:
Source (Host):YeastSpecies:Canine
Product nameRecombinant Canine Erythropoietin
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Cat.#:EPO-3602ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish EPO
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Cat.#:EPO-100ETag:
Source (Host):YeastSpecies:Equine
Product nameRecombinant Equine EPO
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Cat.#:EPO-104STag:
Source (Host):YeastSpecies:Pig
Product nameRecombinant Swine EPO
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Cat.#:EPO-605PTag:His/GST
Source (Host):E. coliSpecies:Pig
Product nameRecombinant Pig EPO protein, His & GST-tagged
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Cat.#:EPO-269HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Erythropoietin
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Cat.#:Epo-173MTag:N/A
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse Erythropoietin
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Cat.#:EPO-1450MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse EPO cell lysate
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Cat.#:EPO-592RCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Rat
Product nameRecombinant Rat EPO cell lysate
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Cat.#:Kit-0327Tag:
Source (Host):Species:
Product nameEosinophil Peroxidase Fluorometric Detection Kit
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Cat.#:EPO-41HTag:
Source (Host):Species:Human
Product nameRecombinant Erythropoietin Reference standard
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Cat.#:EPO-P011HTag:
Source (Host):CHOSpecies:Human
Product nameRecombinant Human EPO therapeutic protein
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Involved Pathway

EPO involved in several pathways and played different roles in them. We selected most pathways EPO participated on our site, such as Cytokine-cytokine receptor interaction, HIF- signaling pathway, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with EPO were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
TNFSF12; CCL20A.3; IL11RA2; CXCL1; LOC100033925; IL1A; CSH; CXCR6; CCL2; FLT3LG
HIF- signaling pathway
AKT1; LTBR; IFNGR1; RPS6KB2; ANGPT2; TFRC; PRKCA; CAMK2D; PIK3CD; IL6R
PIK-Akt signaling pathway
PPP2R5E; NFKB1; IFNA10; ITGB7; PIK3CA; ITGB4; IL7R; PKN2; LAMB4; PPP2R5A
Jak-STAT signaling pathway
Il23a; IL9; FHL1; IFNGR1; IFNA21; SOCS3B; LIF; IL12BA; SOCS7; CSH1
Hematopoietic cell lineage
CD4; CD24; ITGA2; GM13305; ITGA5; HLA-DRB5; CD59; CD1B; MME; EPOR

Protein Function

EPO has several biochemical functions, for example, erythropoietin receptor binding, hormone activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EPO itself. We selected most functions EPO had, and list some proteins which have the same functions with EPO. You can find most of the proteins on our site.
Function
Related Protein
Function erythropoietin receptor binding
Related Protein RNF41; EPO
Function hormone activity
Related Protein PRL7B1; LEP; PRL2A1; STC2; SST1.1; FNDC5; EDN1; UTS2; CRH; POMC
Function protein binding
Related Protein ORC6L; UCP3; PLIN3; SDCCAG3; CASP2; CD6; PRH1; FGFBP1; MGST1; PDE4D
Function protein kinase activator activity
Related Protein DBF4B; NKX3-1; MT3; STRADA; STK11; GPRC5B; NCKAP1L; FGF13; DUSP19; PIK3CA

Interacting Protein

EPO has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EPO here. Most of them are supplied by our site. Hope this information will be useful for your research of EPO.
EPOR; DOK2; EP300

EPO Related Articles

Wiedenmann, T; Ehrhardt, S; et al. Erythropoietin acts as an anti-inflammatory signal on murine mast cells. MOLECULAR IMMUNOLOGY 65:68-76(2015).
Fatemi, MJ; Emami, AH; et al. Effects of Recombinant Human Erythropoietin on Revascularization of Full Thickness Skin Grafts in Rat. IRANIAN RED CRESCENT MEDICAL JOURNAL 16:-(2015).