il28a
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  • Official Full Name
  • interleukin 28A (interferon, lambda 2)
  • Background
  • This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
  • Synonyms
  • IL28A; interleukin 28A (interferon, lambda 2); interleukin 28A; interleukin-28A; IFNL2; IL 28A; IFN-lambda-2; cytokine Zcyto20; interferon lambda 2; interferon lambda-2; interferon-lambda 2; IL-28A
Cat.#:Il28a-5202MTag:
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Il28a Protein
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Cat.#:IL28A-136HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL28A protein
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Cat.#:IL28A-29785THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL28A
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Cat.#:IL28A-311HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human IL28A, MIgG2a Fc-tagged
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Cat.#:IL28A-312HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human IL28A, HIgG1 Fc-tagged
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Cat.#:IL28A-313HTag:Fc
Source (Host):CHOSpecies:human
Product nameRecombinant Human IL28A, Fc-tagged
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Cat.#:IL28A-8162MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse IL28A Protein
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Cat.#:IL28A-131HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human Interleukin 28A (interferon, lambda 2)
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Cat.#:IL28A-539HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Interleukin 28A
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Cat.#:IL28A-221HTag:His
Source (Host):NS0Species:Human
Product nameRecombinant Human Interleukin 28A (Interferon, Lambda 2), His-tagged
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Cat.#:II28A-992MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Murine Interleukin 28A
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Cat.#:Il28a-229MTag:N/A
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse Interleukin 28a
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Cat.#:IL28A-5229HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human IL28A 293 Cell Lysate
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Involved Pathway

IL28A involved in several pathways and played different roles in them. We selected most pathways IL28A participated on our site, such as Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL28A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
IL20; IL15; IL23; INHBC; IL22RA1; IL28RA; CCL19B; TNFRSF17; TNFRSF11B; CXCR5
Jak-STAT signaling pathway
RAF1A; AKT2L; IL13RA1; CSH; STAT4; IL28RA; IRX1; STAT1; FHL1; FHL1A

Protein Function

IL28A has several biochemical functions, for example, cytokine activity, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL28A itself. We selected most functions IL28A had, and list some proteins which have the same functions with IL28A. You can find most of the proteins on our site.
Function
Related Protein
Function cytokine activity
Related Protein Cxcl15; SP100; IL36G; TGFB1A; IL23; IL17A/F2; IFNE; TGFB3; IL16; RNF207B
Function receptor binding
Related Protein HFE; KCNA5; LYN; IAPP; PVRL4; FGF10A; NXPH1; SERPINE1; IZUMO1; FGF1A

IL28A Related Articles

Zhang, LL; Jilg, N; et al. IL28B inhibits hepatitis C virus replication through the JAK-STAT pathway. JOURNAL OF HEPATOLOGY 55:289-298(2011).

IL28A Related Gene Family

IL