Recombinant Mouse Interleukin 28a

• Cat.No.: Il28a-229M

Specification

• Species: Mouse
• Source: Mammalian Cells
• Tag: Non
• Description: Interleukin-28A (IL-28A) also known as IFNL2 is a novel cytokine that exerts its biological effects through a receptor that also binds IL28B and IL29. IL28A induces phosphorylation of STAT1, STAT2, and STAT3 IL-28A has antiviral activities and stimulates antiviral responses through a heterodimeric receptor. IL-28A represents a potential novel approach for therapy of Th1-mediated inflammatory diseases such as T-cell-mediated hepatitis.
• Molecular Weight: The predicted molecular weight of Recombinant Mouse IL-28A is Mr 20.5 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 25-30 kDa.
• State Of Matter: Lyophilized.
• Purity: >95% by SDS Page and analyzed by silver stain.
• Endotoxin: <1.0 EU/µg as determined by the LAL method.
• Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Gene Information

• Gene Name: Il28a interleukin 28A [ Mus musculus ]
• Synonyms: Il28a; interleukin 28A; Ifnl2; EG330496; IFN-lambda2; interferon-lambda2
• Gene ID: 330496
• mRNA Refseq: NM_001024673
• Protein Refseq: NP_001019844
• UniProt ID: Q4VK74
• Chromosome Location: 7
• Pathway: Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway
• Function: cytokine activity