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Recombinant Mouse Interleukin 28a

Cat.No. : Il28a-229M
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Cat. No. : Il28a-229M
Description : Interleukin-28A (IL-28A) also known as IFNL2 is a novel cytokine that exerts its biological effects through a receptor that also binds IL28B and IL29. IL28A induces phosphorylation of STAT1, STAT2, and STAT3 IL-28A has antiviral activities and stimulates antiviral responses through a heterodimeric receptor. IL-28A represents a potential novel approach for therapy of Th1-mediated inflammatory diseases such as T-cell-mediated hepatitis.
Source : Mammalian cells
Molecular Weight : The predicted molecular weight of Recombinant Mouse IL-28A is Mr 20.5 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 25-30 kDa.
State Of Matter : Lyophilized.
Purity : >95% by SDS Page and analyzed by silver stain.
Endotoxin : <1.0 EU/µg as determined by the LAL method.
Storage And Stability : This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Tag : Non
Gene Name : Il28a interleukin 28A [ Mus musculus ]
Synonyms : Il28a; interleukin 28A; Ifnl2; EG330496; IFN-lambda2; interferon-lambda2
Gene ID : 330496
mRNA Refseq : NM_001024673
Protein Refseq : NP_001019844
UniProt ID : Q4VK74
Chromosome Location : 7
Pathway : Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway
Function : cytokine activity

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
11/15/2022

    No need to prepare a special environment, storage conditions are very simple, can be stored for a long time.

    10/04/2020

      Very stable, strong anti-pollution ability, the experimental results are very good.

      07/16/2019

        The labeling effect is very good, and fluorescent labeling can be carried out.

        Q&As (6)

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        What is the main mechanism of action of IL28A? 05/24/2021

        It can enhance the body's immunity to pathogens by activating the immune system.

        What is the role IL28A on the immune system? 03/11/2021

        IL28A regulates the activity and differentiation of immune cells and enhances the function of the immune system.

        What are the pharmacokinetic characteristics of IL28A? 03/09/2021

        It has a long half-life and low clearance, which can maintain a stable plasma concentration.

        How's the progress of clinical trials of IL28A? 06/20/2020

        IL28A is undergoing several clinical trials and is currently showing some efficacy.

        How the synthesis and purification method of IL28A? 06/19/2020

        This protein is usually synthesized using recombinant DNA technology and purified by column chromatography and other methods.

        What are the application prospects of IL28A in tumor therapy? 08/10/2019

        IL28A can regulate immune response and enhance anti-tumor immunity in tumor therapy.

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