ncr3
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  • Official Full Name
  • natural cytotoxicity triggering receptor 3
  • Background
  • The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5 untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • NCR3; natural cytotoxicity triggering receptor 3; LY117, lymphocyte antigen 117; 1C7; CD337; NKp30; Natural killer cell p30 related protein; CD337 antigen; LY117; Lymphocyte antigen 117; NK-p30; OTTHUMP00000029162; OTTHUMP00000029163; OTTHUMP00000029164; OTTHUMP00000029165; activating NK-A1 receptor; activating natural killer receptor p30; natural killer cell p30-related protein; MALS
Cat.#:NCR3-498CTag:His
Source (Host):HEK293Species:Cynomolgus
Product nameRecombinant Cynomolgus NCR3 Protein, His-tagged
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Cat.#:NCR3-100HTag:T7/His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NCR3 protein, T7/His-tagged
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Cat.#:NCR3-486HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human natural cytotoxicity triggering receptor 3, His-tagged
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Cat.#:NCR3-5087HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NCR3, His-tagged
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Cat.#:NCR3-643HTag:Fc
Source (Host):Human cellsSpecies:Human
Product nameRecombinant Human NCR3, Fc-tagged, Biotinylated
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Cat.#:NCR3-814HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human NCR3 Protein, Fc-tagged
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Cat.#:NCR3-815HTag:FC/His
Source (Host):HEK293Species:Human
Product nameRecombinant Human NCR3, Fc-His tagged
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Cat.#:NCR3-816HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human NCR3, His tagged
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Cat.#:Ncr3-1158RTag:His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Ncr3 Protein, His-tagged
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Cat.#:Ncr3-1816RTag:His/T7
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Ncr3 protein, His & T7-tagged
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Cat.#:NCR3-2961RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey NCR3 Protein, His-tagged
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Cat.#:NCR3-2652HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human NCR3 cell lysate
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Involved Pathway

NCR3 involved in several pathways and played different roles in them. We selected most pathways NCR3 participated on our site, such as Natural killer cell mediated cytotoxicity, which may be useful for your reference. Also, other proteins which involved in the same pathway with NCR3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Natural killer cell mediated cytotoxicity
MAPK1; PRKCB; KLRK1; KLRC1; PPP3R1; BRAF; SHC1; HLA-G; PIK3R2; KIR2DL4

Protein Function

NCR3 has several biochemical functions, for example, cell adhesion molecule binding, protein homodimerization activity, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NCR3 itself. We selected most functions NCR3 had, and list some proteins which have the same functions with NCR3. You can find most of the proteins on our site.
Function
Related Protein
Function cell adhesion molecule binding
Related Protein TENM2; CADM2; DSP; EZR; NPTN; CD1D; PVRL2; ADAM8; CADM1B; ITGB2
Function protein homodimerization activity
Related Protein SDCBP; FLT3LG; EVLA; GPD1C; CD226; TCF3B; TBX1; GOLGA5; XPNPEP1; PVR
Function receptor activity
Related Protein TNFRSF13B; SELS; ITGAX; VMN1R44; CADM4; PVRL3B; GRIN2A; VMN1R48; CD200; CLEC4M
Function receptor binding
Related Protein HTT; FGF18B; BLK; FYNA; SSFA2; MYO1C; LGI1; POMC; ZAP70; PVRL1A