PRL
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Official Full Name
prolactin
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Overview
This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. -
Synonyms
PRL; prolactin; decidual prolactin; Prolactin;
- Recombinant Proteins
- Transfected Stable Cell Lines
- Native Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Bovine
- Cattle
- Chicken
- Horse
- Human
- Mouse
- Ovine
- Pig
- Rabbit
- Rat
- Rhesus Macaque
- Sheep
- Zebrafish
- E. coli
- E. Coli
- E.coli
- HEK293
- HEK293 cells
- HEK293F
- HEK293T
- Human Cell
- Human Pituitary Gland
- Insect Cell
- Insect Cells
- Mammalian cell
- Mammalian Cell
- Murine C127 Cell
- P.pastoris
- Sheep Pituitary
- Yeast
- Avi|Fc
- C
- His
- hFc
- His (Fc)
- Avi
- His|GST
- His|SUMO
- His|T7
- Met
- mFc
- Myc
- DDK
- Myc|DDK
- N/A
- N
- GST
- Strep II
- Involved Pathway
- Protein Function
- Interacting Protein
- PRL Related Articles
PRL involved in several pathways and played different roles in them. We selected most pathways PRL participated on our site, such as Cytokine-cytokine receptor interaction, Neuroactive ligand-receptor interaction, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Cytokine-cytokine receptor interaction | IL24;CCL17;CCR6A;MPL;IL10RB;Ccl21c;IL18RAP;Ccl12;GM13306 |
Neuroactive ligand-receptor interaction | PTGER1B;GABRB3;CSH;PTGER4;LTB4R2;HTR5A;CHRNB2;HTR2CL1;ADRB3A |
PIK-Akt signaling pathway | PRL;PGF;IL2RB;TEK;FGFR3;IL3RA;GSK3B;LPAR5;IFNAR2 |
Jak-STAT signaling pathway | SOCS6B;RAF1A;CCND3;PTPN2;IFNA1;EPO;IL22RA1;OSM;AOX2P |
Prolactin signaling pathway | MAPK1;SOCS6;STAT5B;MAP2K1;PRP2;NRAS;STAT1;MAPK3;PIK3R3 |
PRL has several biochemical functions, for example, hormone activity, prolactin receptor binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PRL itself. We selected most functions PRL had, and list some proteins which have the same functions with PRL. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
hormone activity | UCN2;TG;GPHA2;LRSAM1;STC1;THPO;SST2;EDN1;ADM |
prolactin receptor binding | GH1;PRL;PRL4A1;HSD17B7 |
protein binding | MOCS3;LCA5;FAM59A;LAMP1;ATXN2;PDZD3;CACFD1;CDC42EP1;PURA |
PRL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRL here. Most of them are supplied by our site. Hope this information will be useful for your research of PRL.
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