Recombinant Human CD70 Protein, GST-Tagged
Cat.No. : | CD70-0851H |
Product Overview : | Human CD70 full-length ORF (AAH00725, 1 a.a. - 193 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 46.86 kDa |
AA Sequence : | MPEEGSGCSVRRRPYGCVLRAALVP LVAGLVICLVVCIQRFAQAQQQLPL ESLGWDVAELQLNHTGPQQDPRLYW QGGPALGRSFLHGPELDKGQLRIHR DGIYMVHIQVTLAICSSTTASRHHP TTLAVGICSPASRSISLLRLSFHQG CTIASQRLTPLARGDTLCTNLTGTL LPSRNTDETFFGVQWVRP |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | CD70 CD70 molecule [ Homo sapiens ] |
Official Symbol : | CD70 |
Synonyms : | CD70; CD70 molecule; CD27LG, TNFSF7, tumor necrosis factor (ligand) superfamily, member 7; CD70 antigen; CD27L; CD27-L; CD27 ligand; Ki-24 antigen; surface antigen CD70; tumor necrosis factor ligand superfamily member 7; tumor necrosis factor (ligand) superfamily, member 7; CD27LG; TNFSF7; |
Gene ID : | 970 |
mRNA Refseq : | NM_001252 |
Protein Refseq : | NP_001243 |
MIM : | 602840 |
UniProt ID : | P32970 |
Products Types
◆ Recombinant Protein | ||
CD70-623H | Recombinant Human CD70 Protein, Fc-tagged | +Inquiry |
CD70-545H | Recombinant Human CD70 Protein, His (Fc)-Avi-tagged | +Inquiry |
CD70-436H | Recombinant Human CD70 Protein (Gln39-Pro193), MIgG1 Fc-tagged | +Inquiry |
CD70-437H | Recombinant Human CD70 Protein (Gln39-Pro193), RIgG Fc-tagged | +Inquiry |
CD70-0849H | Recombinant Human CD70 Protein, His-Flag-StrepII-Tagged | +Inquiry |
◆ Lysates | ||
CD70-1303RCL | Recombinant Rat CD70 cell lysate | +Inquiry |
CD70-2710HCL | Recombinant Human CD70 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
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Q&As (5)
Ask a questionAntibodies, antibody-drug conjugates, and chimeric antigen receptor (CAR) T-cell therapies are being developed to target CD70 in cancer.
CD70-targeted therapies can enhance the body's immune response against cancer cells and potentially lead to more effective treatments.
CD70 expression is often observed in Hodgkin's lymphoma and certain types of T-cell lymphomas.
Challenges include potential toxicities and finding the right balance to target CD70 effectively without harming normal immune functions.
Yes, there are ongoing clinical trials exploring CD70-targeted therapies for various cancer types.
Customer Reviews (3)
Write a reviewTheir collaboration, expertise, and customized solutions contribute to the successful execution of experiments, reliable data generation, and the advancement of scientific knowledge in the field.
the manufacturer's support is crucial for researchers using CD70 protein in trials.
These resources can enhance the efficiency and accuracy of experimental workflows and contribute to successful outcomes.
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