Recombinant Human CD70 protein, His-Flag-tagged

• Cat.No.: CD70-089H
• Product Overview: Recombinant Human CD70 Protein is expressed from mammalian with His and Flag at the N-terminal. It contains Gln50-Pro193 Trimer.

Specification

• Species: Human
• Source: HEK293
• Tag: Flag&His
• Protein Length: It contains Gln50-Pro193 Trimer.
• Description: CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a calculated MW of 51.8kDa. As a result of glycosylation, the protein migrates to 62- 65kDa by Bis-Tris PAGE.
• Endotoxin: Less than 0.001EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: CD70 CD70 molecule [ Homo sapiens ]
• Official Symbol: CD70
• Synonyms: CD70 molecule; CD70; TNFSF7; TNFSF7CD70 antigen; CD27 Ligand; CD27-L; CD27LCD27 ligand; CD27LG; Ki-24 antigen; surface antigen CD70; tumor necrosis factor (ligand) superfamily, member 7; Tumor necrosis factor ligand superfamily member 7
• Gene ID: 970
• mRNA Refseq: NM_001252
• Protein Refseq: NP_001243
• MIM: 602840
• UniProt ID: P32970