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Active Recombinant Full Length Human CD70 Protein, C-Flag-tagged

Cat.No. : CD70-375HFL
Product Overview : Recombinant Full Length Human CD70 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
Source : Mammalian cells
Species : Human
Tag : Flag
Form : 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Bio-activity : In vitro binding assay
Molecular Mass : 20.9 kDa
AA Sequence : MPEEGSGCSVRRRPYGCVLRAALVP LVAGLVICLVVCIQRFAQAQQQLPL ESLGWDVAELQLNHTGPQQD PRLYWQGGPALGRSFLHGPELDKGQ LRIHRDGIYMVHIQVTLAICSSTTA SRHHPTTLAVGICSPASRSI
SLLRLSFHQGCTIASQRLTPLARGD TLCTNLTGTLLPSRNTDETFFGVQW VRPTRTRPLEQKLISEEDLAANDIL DYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining.
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade.
Concentration : >50 ug/mL as determined by microplate BCA method.
Preparation : Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families : ES Cell Differentiation/IPS, Transmembrane
Protein Pathways : Cytokine-cytokine receptor interaction
Gene Name : CD70 CD70 molecule [ Homo sapiens (human) ]
Official Symbol : CD70
Synonyms : CD27L; LPFS3; CD27-L; CD27LG; TNFSF7; TNLG8A
Gene ID : 970
mRNA Refseq : NM_001252.5
Protein Refseq : NP_001243.1
MIM : 602840
UniProt ID : P32970

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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