|Official Full Name||chemokine (C-X-C motif) ligand 13|
|Background||C-X-C motif chemokine 13 (CXCL13), also known as B lymphocyte chemoattractant (BLC) and B cell-attracting chemokine 1 (BCA-1), is a 109 amino acid secreted protein that belongs to the intercrine alpha (chemokine CxC) family. It functions as a chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. CXCL13 does not induce calcium release in B-lymphocytes. It binds to BLR1/CXCR5. The highest level of CXCL13 is found in the liver, followed by spleen, lymph node, appendix and stomach. Low level of CXC13 is found in salivary gland, mammary gland, and fetal spleen.|
|Synonyms||ANGIE; ANGIE2; BCA-1; BCA1; BLC; BLR1L; SCYB13; B-cell chemoattractant; B-cell-attracting chemokine 1; B-cell-homing chemokine (ligand for Burkitts lymphoma receptor-1); B-lymphocyte chemoattractant; C-X-C motif chemokine 13; CXC chemokine BLC; b cell-attracting chemokine 1; b lymphocyte chemoattractant; chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant); small inducible cytokine B subfamily (Cys-X-Cys motif), member 13 (B-cell chemoattractant); small-inducible cytokine B13|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
CXCL13 involved in several pathways and played different roles in them. We selected most pathways CXCL13 participated on our site, such as CXCR3-mediated signaling events, Chemokine receptors bind chemokines, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CXCL13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|CXCR3-mediated signaling events||CXCL13; MAPKAP1; DNM1|
|Chemokine receptors bind chemokines||CCR5; CCR1; CCBP2; CCR8; ACKR4; CCL27; CX3CR1; AMCF-II; CCR3; CXCR7B|
|Chemokine signaling pathway||CX3CR1; NFKBIA; GNG7; CXCR5; ROCK2; CXCL14; NCF1; HRAS; CCL7; GNAI3|
|Class A/1 (Rhodopsin-like receptors)||RHOL; ADORA2B; CCR5; CYSLTR1; NMU; OXGR1; INSL5; MLN; LPAR1; DRD2|
|Cytokine-cytokine receptor interaction||CCL4L1; IL19; TGFBR1; IRX1; TGFBR1A; OSM; IL1R1; Flt3l; CCL23; CCL7|
|G alpha (i) signalling events||CCR3; RLN3A; INSL5; NMUR1; CHRM2; OXER1; PENKA; APLN; TAS2R13; RGS7|
|GPCR downstream signaling||FGD2; GAL; ARHGAP4A; OBSCN; OR2AP1; LPAR2B; NPB; AGT; GCGA; SST|
|GPCR ligand binding||GPBAR1; PROK2; LPAR2B; EDN1; GPR31B; PTHLH; CRHR1; GPR77; OPN4; SST1.1|
CXCL13 has several biochemical functions, for example, CCR10 chemokine receptor binding, CXCR3 chemokine receptor binding, CXCR5 chemokine receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CXCL13 itself. We selected most functions CXCL13 had, and list some proteins which have the same functions with CXCL13. You can find most of the proteins on our site.
|CCR10 chemokine receptor binding||CCL25; CXCL13; CCL19|
|CXCR3 chemokine receptor binding||CXCL9; PF4; CXCL11; CXCL11.8; CXCL10; CXCL13|
|CXCR5 chemokine receptor binding||CXCL13|
|chemokine activity||CCL11; Cxcl15; IL-8; IL8L2; CXCL16; CCL34B.9; CCL25B; CCL18; CCL35.2; CCL38A.5|
|fibroblast growth factor binding||TGFBR3; PTPRZ1; HSPA9; FGFR2; S100A13; SCN5A; FGFR1; FIBP; FGFR3; FGFR1A|
|heparin binding||SERPINE2; VEGFAA; ADAMTSL5; APPA; PLA2G5; FGF14; VEGFB; WISP1A; THBS1; EPYC|
|protein heterodimerization activity||TIRAP; SAE1; SYT10; HIST1H2A9; IKZF3; HEXA; PBX1; MYF6; HIST1H2AF; WHRN|
|receptor agonist activity||WNT2; GAS6; WNT8A; SFRP2; WNT3A; WNT1; WNT5A; NODAL; VEGFA; WNT4|
CXCL13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CXCL13 here. Most of them are supplied by our site. Hope this information will be useful for your research of CXCL13.