Active Recombinant Human CXCL13 Protein

• Cat.No.: CXCL13-024H
• Product Overview: Purified recombinant protein of Human chemokine (C-X-C motif) ligand 13 (CXCL13)(Val23-Arg94) was expressed in E. coli.

Specification

• Description: Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. Does not induce calcium release in B-lymphocytes. Binds to BLR1/CXCR5. [UniProtKB/Swiss-Prot Function]
• Source: E. coli
• Species: Human
• Bio-activity: Bioactivity was measured by its property to chemoattract Baf3-hCXCR5 transfectants in a dose dependent manner.
• Molecular Mass: 8.6 kDa
• Endotoxin: Less than 0.01 ng per µg protein as determined by the LAL method.
• Purity: > 98% as determined by Coomassie stained SDS-PAGE.
• Concentration: Protein formulated and vialed at >50 µg/mL in specified buffer
• Storage Buffer: 1 x PBS

Gene Information

• Gene Name: CXCL13 chemokine (C-X-C motif) ligand 13 [ Homo sapiens ]
• Official Symbol: CXCL13
• Synonyms: CXCL13; chemokine (C-X-C motif) ligand 13; SCYB13, small inducible cytokine B subfamily (Cys X Cys motif), member 13 (B cell chemoattractant); C-X-C motif chemokine 13; ANGIE; ANGIE2; B cell chemoattractant; BCA 1; BLC; BLR1L; CXC chemokine BLC; B-cell chemoattractant; B-lymphocyte chemoattractant; b lymphocyte chemoattractant; small-inducible cytokine B13; B-cell-attracting chemokine 1; b cell-attracting chemokine 1; chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant); B-cell-homing chemokine (ligand for Burkitts lymphoma receptor-1); small inducible cytokine B subfamily (Cys-X-Cys motif), member 13 (B-cell chemoattractant); BCA1; BCA-1; SCYB13
• Gene ID: 10563
• mRNA Refseq: NM_006419
• Protein Refseq: NP_006410
• MIM: 605149
• UniProt ID: O43927