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Recombinant human CXCL13, His-tagged
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Cat.No. : | CXCL13-2437H Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant human CXCL13 protein, fused to His-tag at N-terminus, was expressed in E.coli |
Description : | B lymphocyte chemoattractant, independently cloned and named Angie, is a CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyer's patches. It preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor 1 (BLR-1). It may therefore function in the homing of B lymphocytes to follicles. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea |
Molecular Mass : | 12.7kDa (110aa) |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSVLEVYYT SLRCRCVQES SVFIPRRFID RIQILPRGNG CPRKEIIVWK KNKSIVCVDP QAEWIQRMMEVLRKRSSSTL PVPVFKRKIP |
Purity : | >85 % by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.25 mg/ml (determined by Bradford assay) |
Gene Name : | CXCL13 chemokine (C-X-C motif) ligand 13 [ Homo sapiens ] |
Official Symbol : | CXCL13 |
Synonyms : | CXCL13; chemokine (C-X-C motif) ligand 13; SCYB13, small inducible cytokine B subfamily (Cys X Cys motif), member 13 (B cell chemoattractant); C-X-C motif chemokine 13; ANGIE; ANGIE2; B cell chemoattractant; BCA 1; BLC; BLR1L; CXC chemokine BLC; B-cell chemoattractant; B-lymphocyte chemoattractant; b lymphocyte chemoattractant; small-inducible cytokine B13; B-cell-attracting chemokine 1; b cell-attracting chemokine 1; chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant); B-cell-homing chemokine (ligand for Burkitts lymphoma receptor-1); small inducible cytokine B subfamily (Cys-X-Cys motif), member 13 (B-cell chemoattractant); BCA1; BCA-1; SCYB13; |
Gene ID : | 10563 |
mRNA Refseq : | NM_006419 |
Protein Refseq : | NP_006410 |
MIM : | 605149 |
UniProt ID : | O43927 |
Chromosome Location : | 4q21 |
Pathway : | CXCR3-mediated signaling events, organism-specific biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; |
Function : | CCR10 chemokine receptor binding; CXCR3 chemokine receptor binding; CXCR5 chemokine receptor binding; chemokine activity; fibroblast growth factor binding; heparin binding; protein heterodimerization activity; receptor agonist activity; |
◆ Recombinant Protein
CXCL13-58H | Recombinant Human CXCL13 Protein | +Inquiry |
CXCL13-2161H | Recombinant Human CXCL13 Protein, GST-tagged | +Inquiry |
Cxcl13-2392M | Recombinant Mouse Cxcl13 Protein | +Inquiry |
Cxcl13-149M | Recombinant Mouse Cxcl13 Protein | +Inquiry |
CXCL13-132H | Recombinant Human CXCL13 Protein | +Inquiry |
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◆ Lysates
CXCL13-7170HCL | Recombinant Human CXCL13 293 Cell Lysate | +Inquiry |
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CXCL1Cxcl10CXCL11CXCL12CXCL13CXCL14Cxcl15Cxcl16Cxcl2CXCL3Cxcl5CXCL6CXCL9Cxcl17CXCL7
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