Recombinant Human EPCAM Protein, Fc-tagged

• Cat.No.: EPCAM-222H
• Product Overview: Recombinant human EPCAM protein with Fc tag was expressed in HEK293.

Specification

• Description: This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.
• Source: HEK293
• Species: Human
• Tag: Fc
• Form: Lyophilized
• Molecular Mass: 54 kDa
• Protein Length: 314
• AA Sequence: MAPPQVLAFGLLLAAATATFAAAQE ECVCENYKLAVNCFVNNNRQCQCTS VGAQNTVICSKLAAKCLVMKAEMNG SKLGRRAKPEGALQNNDGLYDPDCD ESGLFKAKQCNGTSMCWCVNTAGVR RTDKDTEITCSERVRTYWIIIELKH KAREKPYDSKSLRTALQKEITTRYQ LDPKFITSILYENNVITIDLVQNSS QKTQNDVDIADVAYYFEKDVKGESL FHSKKMDLTVNGEQLDLDPGQTLIY YVDEKAPEFSMQGLKAGVIAVIVVV VIAVVAGIVVLVISRKKRMAKYEKA EIKEMGEMHRELNA
• Purity: > 98%
• Applications: WB; ELISA; FACS; FC
• Stability: This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use.
• Storage: At -20 centigrade.
• Concentration: 1 mg/mL
• Storage Buffer: PBS (pH 7.4-7.5). Sterile-filtered colorless solution.
• Reconstitution: Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.

Gene Information

• Gene Name: EPCAM epithelial cell adhesion molecule [ Homo sapiens (human) ]
• Official Symbol: EPCAM
• Synonyms: EPCAM; epithelial cell adhesion molecule; antigen identified by monoclonal AUA1 , M4S1, MIC18, TACSTD1, tumor associated calcium signal transducer 1; 17 1A; 323/A3; CD326; CO 17A; EGP 2; EGP34; EGP40; Ep CAM; ESA; GA733 2; HEA125; KS1/4; KSA; Ly74; MH99; MK 1; MOC31; TACST 1; TROP1; epithelial glycoprotein 314; human epithelial glycoprotein-2; cell surface glycoprotein Trop-1; adenocarcinoma-associated antigen; tumor-associated calcium signal transducer 1; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein); M4S1; MK-1; DIAR5; EGP-2; MIC18; EGP314; HNPCC8; TACSTD1; GA733-2
• Gene ID: 4072
• mRNA Refseq: NM_002354
• Protein Refseq: NP_002345
• MIM: 185535
• UniProt ID: P16422