Recombinant Human GPC3 Protein, Fc-tagged
Cat.No. : | GPC3-621H |
Product Overview : | Human Glypican 3, Fc Tag, low endotoxin is expressed from human 293 cells (HEK293). It contains AA Gln 25 - His 559 (Accession # P51654-1). |
- Specification
- Gene Information
- Related Products
Description : | Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. |
Source : | HEK293 |
Species : | Human |
Tag : | Fc |
Predicted N Terminal : | Gln 25 & Ser 359 |
Form : | Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization. |
Molecular Mass : | This protein carries a human IgG1 Fc tag at the C-terminus. This protein contains a furin-like convertase cleavage site, 355-RQYR-358, and will be partially processed into N and C-terminal fragment with calculated MW of 38.1 kDa and 49.3 kDa respectively. The protein migrates as 40 kDa, 60 kDa and 100-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | Gln 25 - His 559 |
Endotoxin : | Less than 0.1 EU per μg by the LAL method. |
Purity : | >90% as determined by SDS-PAGE |
Storage : | For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | GPC3 glypican 3 [ Homo sapiens ] |
Official Symbol : | GPC3 |
Synonyms : | GPC3; OCI5; Glypican-3; GTR2-2; MXR7; DGSX; SDYS ; SGB; SGBS; SGBS1 |
Gene ID : | 2719 |
mRNA Refseq : | NM_001164617 |
Protein Refseq : | NP_001158089 |
MIM : | 300037 |
UniProt ID : | P51654 |
Products Types
◆ Recombinant Protein | ||
GPC3-269C | Recombinant Cynomolgus monkey GPC3 Protein, Fc-tagged | +Inquiry |
GPC3-271H | Recombinant Human GPC3 Protein, His-tagged | +Inquiry |
GPC3-14H | Recombinant Human GPC3 Protein, C-6His-Avi tagged, Biotinylated | +Inquiry |
GPC3-22H | Recombinant Human GPC3 Protein (25-559aa), C-His-tagged | +Inquiry |
Gpc3-272M | Recombinant Mouse Gpc3 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
GPC3-001MCL | Recombinant Mouse GPC3 cell lysate | +Inquiry |
GPC3-2538HCL | Recombinant Human GPC3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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