HGF

  • Official Full Name

    hepatocyte growth factor (hepapoietin A; scatter factor)

  • Overview

    Hepatocyte growth factor/scatter factor (HGF/SF) is a paracrine cellular growth, motility and morphogenic factor. It is secreted by mesenchymal cells and targets and acts primarily upon epithelial cells and endothelial cells, but also acts on haemopoietic progenitor cells. It has been shown to have a major role in embryonic organ development, in adult organ regeneration and in wound healing.
  • Synonyms

    SF; HGFB; HPTA; F-TCF; DFNB39;Fibroblast derived tumor cytotoxic factor; Hepatocyte growth factor; Hepatocyte growth factor beta chain; Hepatocyte growth factor precursor; Hepatopoeitin-A; Hepatopoietin A; Hgf; Lung fibroblast derived mitogen; OTTHUMP00000161349; OTTHUMP00000206710; OTTHUMP00000206711; OTTHUMP00000206712; OTTHUMP00000206713; OTTHUMP00000206730; Scatter factor; Rilotumumab; 872514-65-3; Flanvotumab; 1188277-05-5;

  • Recombinant Proteins
  • GMP Proteins
  • Cell & Tissue Lysates
  • Transfected Stable Cell Lines
  • Native Proteins
  • Protein Pre-coupled Magnetic Beads
  • Bovine
  • Canine
  • Chicken
  • Cynomolgus
  • Cynomolgus Monkey
  • Dog
  • Human
  • Monkey
  • Mouse
  • Pig
  • Rabbit
  • Rat
  • CHO
  • CHO-K1
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • Hi-5 Inscet Cell
  • Human
  • Human Cell
  • Human cells
  • Insect Cell
  • Insects cell
  • Mammalian Cell
  • Mammalian cells
  • NS0
  • Pig Liver
  • Sf21 Insect Cell
  • Sf9 Insect Cell
  • Wheat Germ
  • C
  • His
  • Fc
  • Fc|His
  • Flag
  • GST
  • His (Fc)
  • Avi
  • His|GST
  • His|T7
  • Myc
  • DDK
  • MYC
  • Myc|DDK
  • N/A
  • N
  • no tag
  • Tag Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HGF-195H Active Recombinant Human HGF protein HEK293 N/A
Human HGF-6H Active Recombinant Human HGF Hi-5 Inscet Cell N/A
Human HGF-8535H Active Recombinant Human HGF CHO N/A
Human HGF-501H Active Recombinant Human HGF Hi-5 Inscet Cell N/A
Human HGF-290H Active Recombinant Human HGF Sf9 Insect Cell N/A
Human HGF-01HG Active GMP Recombinant Human HGF Protein CHO-K1
Human HGF-226H Recombinant Human HGF, 495-728aa, His-tagged E.coli His
Human HGF-254H Recombinant Human HGF Protein, MYC/DDK-tagged HEK293 Myc/DDK This gene encodes a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Expression in specific hematopoietic lineages suggests that this protein may play a role in hematopoietic differentiation.
Human HGF-225H Recombinant Human HGF E.coli N/A 32-285aa
Human HGF-364H Recombinant Human HGF, His tagged Human Cell His
Human HGF-627H Recombinant Human Hepatocyte Growth Factor Human N/A
Human HGF-4726H Recombinant Human HGF Protein E.coli N/A
Human HGF-27731TH Recombinant Human HGF, His-tagged E.coli His
Human HGF-123H Recombinant Human Hepatocyte Growth Factor (Hepapoietin A; Scatter factor) CHO N/A
Human HGF-543H Recombinant Human Hepatocyte Growth Factor Insect Cell Fc
Human HGF-4728H Active Recombinant Human HGF Protein Insect Cell N/A
Human HGF-592H Recombinant Human Hepatocyte Growth Factor (Hepapoietin A; Scatter Factor) HEK293 N/A
Human HGF-4729H Recombinant Human HGF Protein, GST-tagged Wheat Germ GST
Human HGF-792H Recombinant Human HGF protein, His & T7-tagged E.coli His/T7 Val495~Ser728 (Accession # P14210)
Human HGF-341H Recombinant Human HGF Mammalian cells N/A
Human HGF-793H Recombinant Human HGF protein, His & GST-tagged E.coli His/GST Gln32~Asn291 (Accession # P14210)
Human HGF-593H Recombinant Human HGF, His-tagged HEK293 His
Human HGF-872H Recombinant Human HGF, None tagged CHO N/A
Human HGF-001HCL Recombinant Human HGF cell lysate CHO N/A
Human HGF-143HG Active GMP Recombinant Human HGF Protein Mammalian cells N/A
Human HGF-114H Recombinant Active Human HGF Protein, Tag Free HEK293 Tag Free
Human HGF-01H Active Recombinant Human HGF Protein HEK293
Human HGF-157H Human Hepatocyte Growth Factor(precursor, rDNA derived) Reference standard Sf21 Insect Cell N/A
Human HGF-872HAF488 Recombinant Human HGF Protein, None-tagged, Alexa Fluor 488 conjugated CHO no tag 697
Human HGF-20H Recombinant Human HGF Protein E.coli
Human HGF-963H Recombinant Human HGF Protein, GST-tagged E.coli N-GST Gln32-Asn291
Human HGF-158H Human Hepatocyte Growth Factor(rDNA derived) Reference standard CHO N/A
Human HGF-29231TH Native Human HGF N/A
Human HGF-18H Active Recombinant Human HGF Protein, Animal Free Human cells
Human HGF-05HG Active Recombinant Human HGF Protein (Gln32-Ser728, Asp384Asn, Asp416Asn, Leu622Ser, His645Arg, Val678Ile), GMP Grade NS0 Gln32-Ser728, Asp384Asn, Asp416Asn, Leu622Ser, His645Arg, Val678Ile
Human HGF-13H Active Recombinant Human HGF Propeptide Protein Insect Cell N/A
Human HGF-115H Recombinant Active Human HGF Protein, Tag Free Insects cell Tag Free
Human HGF-607HFL Active Recombinant Full Length Human HGF Protein, C-Flag-tagged Mammalian cells Flag
Human HGF-1067H-B Recombinant Human HGF Protein Pre-coupled Magnetic Beads HEK293
Human HGF-210H Recombinant Human HGF protein, Fc-tagged HEK293 Fc Gln32-Ser728
Human HGF-267H Active Recombinant Human HGF Protein CHO α-chain: 463 amino acid<br />β-chain: 234 amino acid
Human HGF-2496H Recombinant Human HGF Protein (Tyr28-Val209), N-His tagged E.coli N-His Tyr28-Val209
Human HGF-4235H Recombinant Human HGF Protein (Gln31-Ser723), C-His tagged Mammalian cells C-His Gln31-Ser723
Human HGF-5037H Recombinant Human HGF Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HGF-144HG GMP Recombinant Human HGF Protein, His-tagged HEK293 His DNA sequence encoding Human HGF(P14210) was expressed with His tag at the C-terminal.
Human HGF-872HAF555 Recombinant Human HGF Protein, None-tagged, Alexa Fluor 555 conjugated CHO no tag 697
Human HGF-872HAF647 Recombinant Human HGF Protein, None-tagged, Alexa Fluor 647 conjugated CHO no tag 697
Human HGF-872HF Recombinant Human HGF Protein, None-tagged, FITC conjugated CHO no tag 697
Human HGF-1067H Recombinant Human HGF Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human HGF-2495H Recombinant Human HGF Protein (Gln32-Ser728), C-His tagged Mammalian cells C-His Gln32-Ser728
Mouse Hgf-728M Active Recombinant Mouse Hepatocyte Growth Factor, His-tagged Mammalian cells His
Mouse Hgf-734M Active Recombinant Mouse Hepatocyte Growth Factor Mammalian cells N/A
Mouse HGF-3402M Active Recombinant Mouse HGF protein(Met1-Leu728) HEK293 N/A Met1-Leu728
Mouse Hgf-599M Recombinant Mouse Hgf Insect Cell N/A
Mouse Hgf-257M Recombinant Mouse Hgf Protein Insect Cell N/A
Mouse Hgf-794M Recombinant Mouse Hgf protein, His-tagged E.coli His Asp482~Val710 (Accession # Q08048)
Mouse Hgf-8664M Active Recombinant Mouse Hgf protein(Met1-Leu728), His-tagged HEK293 C-His Met1-Leu728
Mouse Hgf-4731M Active Recombinant Mouse Hgf Protein Insect Cell N/A
Mouse Hgf-8665M Recombinant Mouse Hgf protein(Met1-Leu728) HEK293 N/A Met1-Leu728
Mouse HGF-1210MCL Recombinant Mouse HGF cell lysate Human Cell N/A
Mouse Hgf-4147M Recombinant Mouse Hgf Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Hgf-073M Recombinant Mouse Hgf Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse Hgf-072M Active Recombinant Mouse Hgf Protein Insect Cell
Mouse Hgf-8665MAF555 Recombinant Mouse Hgf Protein, None-tagged, Alexa Fluor 555 conjugated HEK293 N/A 696
Mouse Hgf-8665MAF488 Recombinant Mouse Hgf Protein, None-tagged, Alexa Fluor 488 conjugated HEK293 N/A 696
Mouse Hgf-4147M-B Recombinant Mouse Hgf Protein Pre-coupled Magnetic Beads HEK293
Mouse Hgf-8664MAF555 Recombinant Mouse Hgf Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His 707
Mouse Hgf-8664MAF488 Recombinant Mouse Hgf Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His 707
Mouse Hgf-8665MAF647 Recombinant Mouse Hgf Protein, None-tagged, Alexa Fluor 647 conjugated HEK293 N/A 696
Mouse Hgf-8664MF Recombinant Mouse Hgf Protein, His-tagged, FITC conjugated HEK293 His 707
Mouse Hgf-8665MF Recombinant Mouse Hgf Protein, None-tagged, FITC conjugated HEK293 N/A 696
Mouse Hgf-8664MAF647 Recombinant Mouse Hgf Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His 707
Rat HGF-2836R Recombinant Rat HGF Protein Mammalian Cell His
Rat Hgf-795R Recombinant Rat Hgf protein, His-tagged E.coli His Cys306~Glu471
Rat Hgf-1237R Recombinant Rat Hgf Protein, GST-tagged E.coli GST
Rat Hgf-8806R Recombinant Rat Hgf protein(Met1-Leu728) HEK293 N/A Met1-Leu728
Rat HGF-1233RCL Recombinant Rat HGF cell lysate Human Cell N/A
Rat HGF-2491R Recombinant Rat HGF Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Hgf-8806RF Recombinant Rat Hgf Protein, None-tagged, FITC conjugated HEK293 no tag 698
Rat HGF-2491R-B Recombinant Rat HGF Protein Pre-coupled Magnetic Beads HEK293
Rat Hgf-8806RAF488 Recombinant Rat Hgf Protein, None-tagged, Alexa Fluor 488 conjugated HEK293 no tag 698
Rat Hgf-8806RAF647 Recombinant Rat Hgf Protein, None-tagged, Alexa Fluor 647 conjugated HEK293 no tag 698
Rat Hgf-8806RAF555 Recombinant Rat Hgf Protein, None-tagged, Alexa Fluor 555 conjugated HEK293 no tag 698
Monkey HGF-152CAF555 Recombinant Cynomolgus HGF Protein, None-tagged, Alexa Fluor 555 conjugated HEK293 N/A 697
Monkey HGF-152CF Recombinant Cynomolgus HGF Protein, None-tagged, FITC conjugated HEK293 N/A 697
Monkey HGF-152CAF488 Recombinant Cynomolgus HGF Protein, None-tagged, Alexa Fluor 488 conjugated HEK293 N/A 697
Monkey HGF-152CAF647 Recombinant Cynomolgus HGF Protein, None-tagged, Alexa Fluor 647 conjugated HEK293 N/A 697
Rabbit HGF-796R Recombinant Rabbit HGF protein, His & T7-tagged E.coli His/T7 Gln32~Arg494 (Accession # C9E9X4)
Dog HGF-791D Recombinant Dog HGF protein, His & T7-tagged E.coli His/T7 Val495~Ser730 (Accession # Q867B7)
Dog HGF-1045CAF647 Recombinant Canine HGF Protein, Alexa Fluor 647 conjugated HEK293 699
Dog HGF-1045CAF555 Recombinant Canine HGF Protein, Alexa Fluor 555 conjugated HEK293 699
Dog HGF-1045CF Recombinant Canine HGF Protein, FITC conjugated HEK293 699
Dog HGF-1045CAF488 Recombinant Canine HGF Protein, Alexa Fluor 488 conjugated HEK293 699
Bovine HGF-322B Recombinant Bovine HGF protein(32-494aa), His-tagged E.coli N-His 32-494aa
Bovine HGF-03B Active Recombinant Bovine HGF Protein, NK1 isoform, Animal-Free E. coli
Canine HGF-1045C Recombinant Canine HGF protein(Met1-Ser730) HEK293 N/A Met1-Ser730
Cynomolgus HGF-146C Active Recombinant Cynomolgus HGF protein HEK293 N/A Met1-Ser728
Cynomolgus Monkey HGF-152C Recombinant Cynomolgus HGF, None tagged Human Cell Fc/His
Cynomolgus Monkey HGF-1077CCL Recombinant Cynomolgus HGF cell lysate Human Cell N/A
Pig HGF-38P Native Porcine HGF Pig Liver N/A
Chicken HGF-2239C Recombinant Chicken HGF Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

HGF involved in several pathways and played different roles in them. We selected most pathways HGF participated on our site, such as Ras signaling pathway, Rap signaling pathway, Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with HGF were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Ras signaling pathwayINS1;SHC3;RASSF1;PIK3CB;PLA2G2F;PLA2G4C;MAP2K1;RASA1;FLT1
Rap signaling pathwayFGF2;FGF12;F2RL3;MAPK3;MAP2K6;ITGAM;INS;PIK3R3;MAGI2
Cytokine-cytokine receptor interactionINHBE;IL3;HGF;AMH;IL20RA;BMPR2;IL4R;IL12BA;IFNA13
PIK-Akt signaling pathwayOSM;CREB3L1;MCL1;GHR;GSK3B;PPP2R3C;TNC;INSR;ITGB7
Focal adhesionFYNA;THBS2;PIK3R3B;MYLK4;MYL7;KDRL;FLNC;THBS4A;AASS
MalariaTGFB2;IL18;CSF3;ITGAL;LRP1;SDC1;SELP;TGFB3;TLR9
Pathways in cancerGNG11;PTCH2;Casp3;PIK3R5;RHOA;LEF1;FH1;WNT5A;IGF1R
Proteoglycans in cancerPIK3CG;MRAS;CAV2;HIF1A;WNT1;CBL;SOS1;SLC9A1;CAMK2G
Renal cell carcinomaPIK3R3;MAP2K2;ARNT;HGF;ARAF;AKT2;CUL2;PIK3CB;PIK3R1
MelanomaPIK3R1;PDGFB;FGFR1;TP53;PIK3CG;HRAS;PIK3R3;FGF16;PDGFRB

HGF has several biochemical functions, for example, chemoattractant activity, growth factor activity, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HGF itself. We selected most functions HGF had, and list some proteins which have the same functions with HGF. You can find most of the proteins on our site.

Function Related Protein
chemoattractant activitySAA3;VEGFC;LGALS3;SAA2;SCG2;HGF;CXCL12B;VEGFA;PDGFB
growth factor activityPSPN;FGF10B;FIGF;FGF6B;GPI1;FGF11;TGFA;NRG2;FGF13
identical protein bindingDAAM1;UBE2G2;ESR1;DVL1;C1QTNF9;HTT;TPCN1;LCK;SOX10
protein bindingUQCC2;PHF7;FANCD2;IL6R;MED23;HSPA9;C10orf137;DCAF11;IREB2
protein heterodimerization activityTYRO3;H3F3A;KCNB2;ADD2;SPTAN1;SMAD2;GABPB2;HIST1H2B5;SPTA1
serine-type endopeptidase activityHTRA3A;KLK1B3;TMPRSS11B;TYSND1;KLK1B4;CLPP;PRSS3;KLK1;PRSS54
NOT serine-type endopeptidase activityHGF;RHBDF2;RHBDF1

HGF has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HGF here. Most of them are supplied by our site. Hope this information will be useful for your research of HGF.

MET; MEOX2; Met; ADAMTSL4; SRPX2; Hgf; FN1; CD44

Research Area

Related articles

Pena-Silva, RA; Chalouhi, N; et al. Novel Role for Endogenous Hepatocyte Growth Factor in the Pathogenesis of Intracranial Aneurysms. HYPERTENSION 65:587-593(2015).
Wang, YQ; Fukuda, T; et al. Loss of alpha 1,6-fucosyltransferase suppressed liver regeneration: implication of core fucose in the regulation of growth factor receptor-mediated cellular signaling. SCIENTIFIC REPORTS 5:-(2015).
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