Active GMP Recombinant Human IL11 protein

Cat.No. : IL11-121HG
Product Overview : GMP Recombinant Human IL11 protein(NP_000632)(184 aa), fused with His Tag at the C-terminal, was expressed in HEK293 cell in an animal component free process under cGMP guidelines.
  • Specification
  • Gene Information
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Source : HEK293
Species : Human
Bio-activity : >=5×10^5 IU/mg
Molecular Mass : Recombinant Human IL-11 contains 184 aa. It has a predicted MW of 20 kDa.
Protein length : DNA sequence encoding Human IL-11(NP_000632.1) was expressed with His tag at the C-terminal.
Endotoxin : <=0.02EU/ug
Purity : >=95% by SDS-PAGE and HPLC
Storage : The lyophilized preparation can be stored at 4°C for 24 months, and the dissolved liquid can be stored at -20°C for 6-12 months to avoid repeated freezing and thawing
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : IL11 interleukin 11 [ Homo sapiens ]
Official Symbol : IL11
Synonyms : IL11; interleukin 11; interleukin-11; adipogenesis inhibitory factor; AGIF; IL 11; oprelvekin; IL-11
Gene ID : 3589
mRNA Refseq : NM_000641
Protein Refseq : NP_000632
MIM : 147681
UniProt ID : P20809

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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How are in vivo models, including transgenic mice and knockdown strategies, utilized to study IL11's effects on tissue regeneration and homeostasis? 11/05/2022

Transgenic mice and knockdown models explore IL11's impact on tissue regeneration.

Could you explain the experimental approaches, such as site-directed mutagenesis, employed to identify key residues in IL11's interaction with IL11RA? 07/14/2021

Site-directed mutagenesis identifies key residues in IL11's interaction with IL11RA.

What techniques like chromatin immunoprecipitation and DNA methylation analysis contribute to deciphering IL11's regulatory mechanisms? 05/27/2021

Chromatin immunoprecipitation and DNA methylation analysis decipher IL11's regulatory mechanisms.

Can you elaborate on the role of proteomics in identifying IL11-interacting proteins and potential cross-talk with other signaling pathways? 09/28/2020

Proteomics identifies IL11-interacting proteins and potential cross-talk partners.

How do cell-based assays and luciferase reporter assays help investigate IL11's downstream signaling pathways through JAK-STAT activation? 05/19/2020

Cell-based and luciferase reporter assays elucidate IL11's JAK-STAT signaling activation.

What role does RNA sequencing play in understanding IL11-induced gene expression changes in various cell types? 02/24/2019

RNA sequencing uncovers IL11-induced gene expression changes across different cell types.

What structural insights have X-ray crystallography and nuclear magnetic resonance spectroscopy provided about the IL11-IL11RA complex? 01/13/2019

X-ray crystallography and NMR spectroscopy reveal structural details of the IL11-IL11RA complex.

How do advanced imaging techniques like confocal microscopy and super-resolution microscopy visualize IL11 localization and distribution in tissues? 11/08/2018

Confocal and super-resolution microscopy visualize IL11 localization in tissues.

How are techniques like surface plasmon resonance used to study IL11's binding kinetics to its receptor IL11RA? 04/17/2017

Techniques like surface plasmon resonance measure IL11-IL11RA binding affinity and kinetics.

What insights have CRISPR screening approaches provided regarding genes and pathways influenced by IL11 signaling? 02/06/2017

CRISPR screening unveils genes and pathways influenced by IL11 signaling.

Customer Reviews (3)

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Reviews
10/28/2019

    Potent in bone regeneration models. -

    11/26/2017

      Suitable for cell culture. -

      01/10/2017

        High yield in expression. -

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