• Official Full Name

    interleukin 25

  • Background

    IL-25 is a cytokine that shares the sequence similarity with IL17. This cytokine can induce NF-κB activation, and stimulate the production of IL8. Both this cytokine and IL17B are ligands for the cytokine receptor IL17RB. Studies of the similar gene in mice suggested that this cytokine may be a proinflammatory cytokine favoring Th2-type immune response. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. IL-25 is a cytokine that belongs to the IL-17 cytokine family and is secreted by type 2 helper T cells (Th2) and mast cells. It is also known as IL-17E.
  • Synonyms

    IL25; interleukin 25; interleukin 17E; IL17E; IL-25; IL-17E; Interleukin-25; UNQ3120/PRO10272; Interleukin-17E;
    • Type:
    • GMP Proteins
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293F
    • HEK293T
    • Human Cell
    • Human Cells
    • Insect Cell
    • Mammalian cells
    • Tag :
    • Fc
    • hFc
    • His
    • His (Fc)
    • Avi
    • His(C
    • ter)
    • His|GST
    • His|T7
    • Met
    • MYC
    • DDK
    • Myc|DDK
    • N/A
    • N
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IL25-136HG GMP Recombinant Human IL25 Protein E.coli N/A
    Human IL25-165H Recombinant Human IL25 Protein E.coli
    Human IL25-2920HCL Recombinant Human IL25 cell lysate Human Cell N/A
    Human IL25-148H Recombinant Human IL25 protein, hFc-tagged HEK293 hFc
    Human IL25-151H Recombinant Human IL25 Protein, His-tagged Human Cells His
    Human IL25-1812H Recombinant Human IL25 protein, His-tagged E.coli His
    Human IL25-153H Recombinant Human IL25 protein, His-tagged HEK293 His
    Human IL25-182H Recombinant Active Human IL25 Protein, His-tagged(C-ter) E.coli His(C-ter)
    Human IL25-509H Recombinant Human IL25 Protein
    Human IL25-140H Recombinant Human Interleukin 25 E.coli N/A
    Human IL25-1926H Recombinant Human IL25 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human IL25-1031H Recombinant Human IL25 Protein, His-tagged HEK293F N-His
    Mouse IL25-166M Recombinant Mouse IL25 Protein E.coli
    Mouse IL25-2910MCL Recombinant Mouse IL25 cell lysate Human Cell N/A
    Mouse Il25-804M Active Recombinant Mouse Il25 E.coli Met
    Mouse Il25-183M Recombinant Active Mouse IL25 Protein, His-tagged(C-ter) E.coli His(C-ter)
    Mouse Il25-10584M-B Recombinant Mouse Il25 Protein Pre-coupled Magnetic Beads HEK293
    Mouse IL25-149M Recombinant Mouse IL25, His tagged Human Cell His
    Mouse Il25-5210M Recombinant Mouse Il25 Protein E.coli N/A
    Mouse Il25-10584M Recombinant Mouse Il25 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Mouse Il25-1010M Recombinant Mouse Il25 Protein Insect Cell
    Mouse Il25-1813M Recombinant Mouse Il25 protein, His & GST-tagged E.coli His/GST
    Mouse Il25-01M Active Recombinant Mouse Il25 Protein, His-Tagged E.coli His
    Mouse Il25-748M Recombinant Mouse Interleukin 25, His-tagged Human Cell His
    Mouse Il25-1011M Recombinant Mouse Il25 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Mouse Il25-805M Active Recombinant Mouse Il25 Mammalian cells N/A
    Mouse Il25-199M Recombinant Mouse Interleukin 25 E.coli N/A
    Mouse IL25-1924M Recombinant Mouse IL25 Protein Insect Cell N/A
    Rat IL25-1261RCL Recombinant Rat IL25 cell lysate Human Cell N/A
    Rat Il25-1814R Recombinant Rat Il25 protein, His & T7-tagged E.coli His/T7
    Rat Il25-90R Recombinant Rat Interleukin 25 E.coli N/A
    Rat Il25-8736R Recombinant Rat Il25, Fc tagged Human Cell Fc
    Rat IL25-5209R Recombinant Rat IL25 Protein E.coli N/A
    Rat IL25-495R Active Recombinant Rat Interleukin-17E (IL-25) E.coli N/A
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • Il25 Related Research Area

    Il25 involved in several pathways and played different roles in them. We selected most pathways Il25 participated on our site, such as Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with Il25 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interactionTNFRSF8;CCR9;LIF;TNFRSF9;TNFSF8;TNFSF12;IFNPHI3;CXCL1;IFNB

    Il25 has several biochemical functions, for example, cytokine activity, interleukin-17E receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Il25 itself. We selected most functions Il25 had, and list some proteins which have the same functions with Il25. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activityGm13290;GPI;LEFTY2;Cxcl15;GREM1A;CMTM6;CCL38A.4;IFNT2;Kitl
    interleukin-17E receptor binding

    Il25 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Il25 here. Most of them are supplied by our site. Hope this information will be useful for your research of Il25.


    • Q&As
    • Reviews

    Q&As (6)

    Ask a question
    Is there any research showing that IL-25 is effective in tumor treatment? 12/10/2022

    There is a lack of conclusive evidence that IL-25 has a clear effect in tumor treatment, but there are some studies underway.

    Are there any side effects to IL-25? 09/22/2021

    There are no clear studies on the side effects of IL-25, but the patient response needs to be closely monitored during research and clinical application.

    Has the study found potential applications of IL-25 in the treatment of other diseases? 01/18/2021

    In addition to treating asthma and inflammatory bowel disease, IL-25 may also have potential applications in the treatment of lung infections, urticaria and other diseases.

    What is the mechanism of action of IL-25? 12/18/2020

    IL-25 activates specific signaling pathways by binding to specific receptors, thereby regulating the activity of immune cells and the degree of inflammation in the body.

    Is there any research showing that IL-25 is effective against certain diseases? 08/17/2020

    Some studies have shown that recombinant IL-25 can improve symptoms of diseases such as asthma and inflammatory bowel disease, but more research is needed to verify its efficacy.

    Does IL-25 therapy need to be administered by injection? 03/28/2019

    Yes, in general, IL-25 therapy needs to be administered by injection to ensure that the protein can enter the body and work.

    Customer Reviews (3)

    Write a review

      Efficacy of the protein can be evaluated by observing its pharmacokinetics, pharmacodynamics and toxicity in mice or rats. -


        Animal models were used to evaluate the efficacy and side effects of the remade proteins. -


          Storage is stable, and the environmental requirements are not harsh. -

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