Active Recombinant Mouse Il25 Protein, His-Tagged Il25-01M

Active Recombinant Mouse Il25 Protein, His-Tagged

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Cat.No. : Il25-01M Optional Service: Optional requirements on this protein
Product Overview : Recombinant mouse Il25 Protein, His-tagged was expressed in E. coli cell
Description : Interleukin-25 (IL-25) is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. IL-25 is a member of the IL-17 family of cytokines. However, unlike the other members of this family, IL-25 promotes T helper (Th) 2 responses. IL-25 also regulates the development of autoimmune inflammation mediated by IL-17–producing T cells. IL-25 and IL-17, being members of the same cytokine family, play opposing roles in the pathogenesis of organ-specific autoimmunity.
Source : Escherichia coli
Species : Mouse
Tag : His
Form : Lyophilized powder
AA Sequence : MVSLRIQEGC SHLPSCCPSK EQEPPEEWLK WSSASVSPPE PLSHTHHAES CRASKDGPLN SRAISPWSYE LDRDLNRVPQ DLYHARCLCP HCVSLQTGSH MDPLGNSVPL YHNQTVFYRR PCHGEEGTHR RYCLERRLYR VSLACVCVRP RVMA with polyhistidine tag at the C-terminus
Endotoxin : <0.1 EU per 1 μg of the protein by the LAL method.
Bio-activity : Measured by its ability to induce CXCL1 secretion in HT‑29 cells. The ED50 for this effect is <1 ng/mL.
Purity : >98% as determined by SDS-PAGE. Ni-NTA chromatography
Storage Buffer : The protein was lyophilized from a solution containing 20 mM sodium citrate, 0.2 M NaCl, pH 4.5.
Reconstitution : It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
Storage : Lyophilized protein should be stored at -20°C. Upon reconstitution, protein aliquots should be stored at -20°C or -80°C.
Notes : Please use within one month after protein reconstitution.
Figure :

Gene Name : Il25 interleukin 25 [ Mus musculus (house mouse) ]
Official Symbol : Il25
Synonyms : Il17e; IL-17e
Gene ID : 140806
mRNA Refseq : NM_080729.3
Protein Refseq : NP_542767.1
UniProt ID : Q8VHH8
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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