Active Recombinant Mouse Il25 Protein, His-Tagged
Cat.No. : | Il25-01M |
Product Overview : | Recombinant mouse Il25 Protein, His-tagged was expressed in E. coli cell |
- Specification
- Gene Information
- Related Products
Description : | Interleukin-25 (IL-25) is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. IL-25 is a member of the IL-17 family of cytokines. However, unlike the other members of this family, IL-25 promotes T helper (Th) 2 responses. IL-25 also regulates the development of autoimmune inflammation mediated by IL-17–producing T cells. IL-25 and IL-17, being members of the same cytokine family, play opposing roles in the pathogenesis of organ-specific autoimmunity. |
Source : | Escherichia coli |
Species : | Mouse |
Tag : | His |
Form : | Lyophilized powder |
AA Sequence : | MVSLRIQEGCSHLPSCCPSKEQEPP EEWLKWSSASVSPPEPLSHTHHAES CRASKDGPLNSRAISPWSYELDRDL NRVPQDLYHARCLCPHC VSLQTGSHMDPLGNSVPLYHNQTVF YRRPCHGEEGTHRRYCLERRLYRVS LACVCVRPRVMA with polyhistidine tag at the C-terminus |
Endotoxin : | <0.1 EU per 1 μg of the protein by the LAL method. |
Bio-activity : | Measured by its ability to induce CXCL1 secretion in HT‑29 cells. The ED50 for this effect is <1 ng/mL. |
Purity : | >98% as determined by SDS-PAGE. Ni-NTA chromatography |
Storage Buffer : | The protein was lyophilized from a solution containing 20 mM sodium citrate, 0.2 M NaCl, pH 4.5. |
Reconstitution : | It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved. |
Storage : | Lyophilized protein should be stored at -20°C. Upon reconstitution, protein aliquots should be stored at -20°C or -80°C. |
Notes : | Please use within one month after protein reconstitution. |
Gene Name : | Il25 interleukin 25 [ Mus musculus (house mouse) ] |
Official Symbol : | Il25 |
Synonyms : | Il17e; IL-17e |
Gene ID : | 140806 |
mRNA Refseq : | NM_080729.3 |
Protein Refseq : | NP_542767.1 |
UniProt ID : | Q8VHH8 |
Products Types
◆ Recombinant Protein | ||
IL25-509H | Recombinant Human IL25 Protein | +Inquiry |
IL25-166M | Recombinant Mouse IL25 Protein | +Inquiry |
Il25-1011M | Recombinant Mouse Il25 Protein, MYC/DDK-tagged | +Inquiry |
Il25-5210M | Active Recombinant Mouse Il25 Protein | +Inquiry |
IL25-182H | Recombinant Active Human IL25 Protein, His-tagged(C-ter) | +Inquiry |
◆ Lysates | ||
IL25-2920HCL | Recombinant Human IL25 cell lysate | +Inquiry |
IL25-2910MCL | Recombinant Mouse IL25 cell lysate | +Inquiry |
IL25-1261RCL | Recombinant Rat IL25 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionThere is a lack of conclusive evidence that IL-25 has a clear effect in tumor treatment, but there are some studies underway.
There are no clear studies on the side effects of IL-25, but the patient response needs to be closely monitored during research and clinical application.
In addition to treating asthma and inflammatory bowel disease, IL-25 may also have potential applications in the treatment of lung infections, urticaria and other diseases.
IL-25 activates specific signaling pathways by binding to specific receptors, thereby regulating the activity of immune cells and the degree of inflammation in the body.
Some studies have shown that recombinant IL-25 can improve symptoms of diseases such as asthma and inflammatory bowel disease, but more research is needed to verify its efficacy.
Yes, in general, IL-25 therapy needs to be administered by injection to ensure that the protein can enter the body and work.
Customer Reviews (3)
Write a reviewThe activity is very strong and can meet my research needs.
Price is very reasonable and good value for money.
It is very stable and can be stored and used for a long time.
Ask a Question for All Il25 Products
Required fields are marked with *
My Review for All Il25 Products
Required fields are marked with *
Inquiry Basket