Active Recombinant Rat IL25 Protein

Cat.No. : IL25-5209R
Product Overview : Rat IL25 recombinant protein expressed in Escherichia coli.
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Description : The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. This cytokine can induce NF-kappaB activation, and stimulate the production of IL8. Both this cytokine and IL17B are ligands for the cytokine receptor IL17BR. Studies of the similar gene in mice suggested that this cytokine may be a proinflammatory cytokine favoring Th2-type immune response. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
Source : E. coli
Species : Rat
Form : Lyophilized
Bio-activity : The activity is determined by the dose-dependent induction of human IL-8 production from human PBMCs. The expected ED50 for this effect is 25-37.5 ng/mL.
Molecular Mass : 35.5 kDa
Endotoxin : < 0.1 EU/μg
Applications : Functional Study
Storage : Store at -20 centigrade on dry atmosphere. After reconstitution with sterilized 20 mM HCl, store at -20 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : No additive
Tag : Non
Gene Name : Il25 interleukin 25 [ Rattus norvegicus ]
Official Symbol : IL25
Synonyms : IL25; interleukin 25; interleukin-25; RGD1561632;
Gene ID : 501996
mRNA Refseq : NM_001192007
Protein Refseq : NP_001178936

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.


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Customer Reviews (3)

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    The activity is very strong and can meet my research needs.


      Price is very reasonable and good value for money.


        It is very stable and can be stored and used for a long time.

        Q&As (6)

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        Is there any research showing that IL-25 is effective in tumor treatment? 12/10/2022

        There is a lack of conclusive evidence that IL-25 has a clear effect in tumor treatment, but there are some studies underway.

        Are there any side effects to IL-25? 09/22/2021

        There are no clear studies on the side effects of IL-25, but the patient response needs to be closely monitored during research and clinical application.

        Has the study found potential applications of IL-25 in the treatment of other diseases? 01/18/2021

        In addition to treating asthma and inflammatory bowel disease, IL-25 may also have potential applications in the treatment of lung infections, urticaria and other diseases.

        What is the mechanism of action of IL-25? 12/18/2020

        IL-25 activates specific signaling pathways by binding to specific receptors, thereby regulating the activity of immune cells and the degree of inflammation in the body.

        Is there any research showing that IL-25 is effective against certain diseases? 08/17/2020

        Some studies have shown that recombinant IL-25 can improve symptoms of diseases such as asthma and inflammatory bowel disease, but more research is needed to verify its efficacy.

        Does IL-25 therapy need to be administered by injection? 03/28/2019

        Yes, in general, IL-25 therapy needs to be administered by injection to ensure that the protein can enter the body and work.

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