Recombinant Human IL25 Protein, His-tagged
|Product Overview :||Recombinant Human IL25 Protein (Tyr33-Gly177) with His tag was expressed in 293F.|
- Gene Information
- Related Products
|Description :||The protein encoded by this gene is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. Studies of a similar gene in mice suggest that this cytokine may be a pro-inflammatory cytokine favoring the Th2-type immune response. Alternative splicing results in multiple transcript variants.|
|Form :||Freeze-dried powder|
|Molecular Mass :||Predicted Molecular Mass: 18.4 kDa; Accurate Molecular Mass: 17&19&21 kDa|
|Protein length :||Tyr33-Gly177|
|Purity :||> 90%|
|Applications :||Positive Control; Immunogen; SDS-PAGE; WB.|
|Stability :||The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.|
|Storage :||Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.|
|Storage Buffer :||PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.|
|Reconstitution :||Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.|
|Gene Name :||IL25 interleukin 25 [ Homo sapiens (human) ]|
|Official Symbol :||IL25|
|Synonyms :||IL25; interleukin 25; IL17E, interleukin 17E; interleukin-25; IL 17E; IL 25; interleukin 17E; interleukin-17E; IL17E;|
|Gene ID :||64806|
|mRNA Refseq :||NM_022789|
|Protein Refseq :||NP_073626|
|UniProt ID :||Q9H293|
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (6)Ask a question
There is a lack of conclusive evidence that IL-25 has a clear effect in tumor treatment, but there are some studies underway.
There are no clear studies on the side effects of IL-25, but the patient response needs to be closely monitored during research and clinical application.
In addition to treating asthma and inflammatory bowel disease, IL-25 may also have potential applications in the treatment of lung infections, urticaria and other diseases.
IL-25 activates specific signaling pathways by binding to specific receptors, thereby regulating the activity of immune cells and the degree of inflammation in the body.
Some studies have shown that recombinant IL-25 can improve symptoms of diseases such as asthma and inflammatory bowel disease, but more research is needed to verify its efficacy.
Yes, in general, IL-25 therapy needs to be administered by injection to ensure that the protein can enter the body and work.
Customer Reviews (3)Write a review
Efficacy of the protein can be evaluated by observing its pharmacokinetics, pharmacodynamics and toxicity in mice or rats. -
Animal models were used to evaluate the efficacy and side effects of the remade proteins. -
Storage is stable, and the environmental requirements are not harsh. -
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