"JAK2" Related Products

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Recombinant Human JAK2 protein, Flag-tagged, Biotinylated

Cat.No.: JAK2-57H
Product Overview: Recombinant Human JAK2, catalytic domain [826-1132(end) amino acids of accession number NP_004963.1] fused with DYKDDDDK tag at N-terminal was expressed in insect cell and biotinylated.
Source: Insect cell
Species: Human
Tag: Flag
Form: 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5
Molecular Mass: 39 kDa
Purity: >85% as determined by SDS-PAGE and CBB staining
Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Gene Name: JAK2 Janus kinase 2 [ Homo sapiens ]
Official Symbol: JAK2
Synonyms: JAK2; Janus kinase 2; tyrosine-protein kinase JAK2; JTK10; JAK-2; THCYT3;
Gene ID: 3717
mRNA Refseq: NM_004972
Protein Refseq: NP_004963
MIM: 147796
UniProt ID: O60674
Chromosome Location: 9p24
Pathway: Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; CXCR4-mediated signaling events, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Cholinergic synapse, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem;
Function: ATP binding; SH2 domain binding; growth hormone receptor binding; heme binding; histone binding; histone kinase activity (H3-Y41 specific); interleukin-12 receptor binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein binding; protein kinase activity; protein kinase binding; protein tyrosine kinase activity; protein tyrosine kinase activity; receptor binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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