Active Human Hemopexin Reference Standard
Cat.No. : | HPX-16H |
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Description : | Hemopexin binds heme with the highest affinity of any known protein. Its performs functions in scavenging the heme released or lost by the turnover of heme proteins such as hemoglobin, thus protects the body from the oxidative damage that free heme can cause. In addition, hemopexin releases its bound ligand for internalisation upon interacting with a specific receptor situated on the surface of liver cells, thus implicated in preservation of the body"s iron. High hemopexin levels indicate that there has been significant degradation of heme containing compounds and hemopexin is made to scavenge any heme it can, and high hemopexin levels are therefore one of the diagnostic features of a hemolytic anemia. |
Species : | Human |
Form : | Liquid |
Bio-activity : | The level of Hemopexin in the serum was quantified using ELISA. |
Usage : | For research use only, not for diagnostic or therapeutic use. |
Quality Control Test : | Generated from a human serum pool. This lot has been tested by standard laboratory procedures and found to be negative for HIV 1, HIV 2, Hepatitis B and Hepatitis C. |
Storage : | Stored at -20 °C, 4 °C for less than seven days, frozen for greater than seven days. |
Concentration : | 1.16 mg/ml |
Preservative : | 0.1% sodium azide |
Tag : | Non |
Gene Name : | HPX hemopexin [ Homo sapiens ] |
Official Symbol : | HPX |
Synonyms : | HPX; hemopexin; beta-1B-glycoprotein; HX; FLJ56652; |
Gene ID : | 3263 |
mRNA Refseq : | NM_000613 |
Protein Refseq : | NP_000604 |
MIM : | 142290 |
UniProt ID : | P02790 |
Chromosome Location : | 11p15.5-p15.4 |
Function : | binding; heme transporter activity; metal ion binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
Hpx-1167M | Recombinant Mouse Hpx Protein, MYC/DDK-tagged | +Inquiry |
HPX-2563R | Recombinant Rat HPX Protein, His (Fc)-Avi-tagged | +Inquiry |
HPX-3122H | Recombinant Human HPX Protein, His (Fc)-Avi-tagged | +Inquiry |
HPX-754H | Recombinant Human HPX protein(Met 1-His 462), His-tagged | +Inquiry |
HPX-1463C | Recombinant Cynomolgus HPX protein, His-tagged | +Inquiry |
◆ Native Protein | ||
HPX-207H | Native Human Hemopexin | +Inquiry |
HPX-206H | Native Human Native Human HPX | +Inquiry |
HPX-29307TH | Native Human Hemopexin | +Inquiry |
◆ Lysates | ||
HPX-2279MCL | Recombinant Mouse HPX cell lysate | +Inquiry |
HPX-2789HCL | Recombinant Human HPX cell lysate | +Inquiry |
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Not For Human Consumption!
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Customer Reviews (3)
Write a reviewthe manufacturer offers a wide range of HPX protein variants, including recombinant or native forms, as well as different conjugates and modifications.
As a researcher using HPX protein, I have found numerous advantages in its application during trials for various experimental purposes.
the HPX protein is known for its strong affinity for phospholipids, particularly phosphatidylserine (PS), on the outer leaflet of cell membranes.
Q&As (5)
Ask a questionYes, low levels of HPX in the blood can be an indicator of hemolytic disorders.
HPX binds to free heme released from hemoglobin, preventing its toxic effects and aiding in its clearance.
HPX binds to heme, preventing its oxidative and inflammatory damage to tissues and organs.
Hemolysis, hemoglobinopathies, and various types of anemias can lead to heme release, highlighting the clinical relevance of HPX.
HPX levels can be influenced by various factors, including inflammation and medications like glucocorticoids.
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