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Active Recombinant Canine Chemokine (C-C motif) Ligand 2

Cat.No. : CCL2-406C
Product Overview : Recombinant Canine CCL2 protein wasexpressed in E. coli. Gln24-Pro101.
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  • Gene Information
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Cat. No. : CCL2-406C
Description : Canine CCL2is an 8 kDa member of the CC chemokine family of chemotactic factors. It issynthesized as a 101 amino acid (aa) precursor that contains a 23 aa signalsequence and a 78 aa mature segment. It contains no potential N-linked glycosylationsites and is not known for any posttranslational modifications.
Source : E. coli
Form : Lyophilizedfrom a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
N-terminal Sequence : Noresults obtained: Gln24 predicted
Molecular Weight : 8.8 kDa
Activity : Measured by itsability to chemo-attract human CCR2A transected BaF3 Canine pro-B cells. TheED50 for this effect is typically 0.03-0.15 μg/mL.
Endotoxin Level : <1.0 EU per 1μgof the protein by the LAL method.
Purity : >95%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution : Reconstitute at 25 μg/mL insterile PBS that containing at least 0.1% human or bovine serum albumin.
Storage : Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month,2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70°C under sterile conditions afterreconstitution.
Gene Name : CCL2 chemokine (C-C motif)ligand 2 [ Canis lupus familiaris ]
Official Symbol : CCL2
Synonyms : CCL2; chemokine(C-C motif) ligand 2; C-C motif chemokin 2; MCP-1; small-inducible cytokineA2; momocyte chemo attractant protein 1; momocyte chemo attractant protein-1;MCP1; SCYA2
Gene ID : 403981
mRNA Refseq : NM_001003297
Protein Refseq : NP_001003297
UniProt ID : P52203
Chromosome Location : 9
Pathway : Chagasdisease (American trypanosomiasis); Chemokine signaling pathway; Cytokine-cytokinereceptor interaction; Diabetes pathways; Herpes simplex infection;Influenza A; Malaria; NOD-like receptor signaling pathway; PERK regulatedgene expression; Rheumatoid arthritis; Unfolded Protein Response

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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