Active Recombinant Canine GM-CSF

• Cat.No.: Csf2-94C

Specification

• Species: Canine
• Source: Yeast
• Tag: Non
• Description: Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a protein secreted by macrophages, T cells, mast cells, NK cells, endothelial cells and fibroblasts. GM-CSF stimulates stem cells to produce granulocytes (neutrophils, eosinophils, and basophils) and monocytes. Granulocyte macrophage–colony stimulating factor (GM-CSF) is secreted in response to inflammatory stimuli such as LPS, IL-1, and TNF-α by a variety of different cells, including endothelium, fibroblasts, muscle cells, and macrophages, and by activated T cells. GM-CSF is glycosylated in its mature form.
• Form: Lyophilized
• Bio-activity: The biological activity of recombinant canine GM-CSF was measured in a cell proliferation assay using the human TF-1 cell line. The ED50 for this effect is typically 25 - 45 ng/mL.
• Molecular Mass: 14.2 kDa
• AA Sequence: APTRSPTLVT RPSQHVDAIQ EALSLLNNSN DVTAVMNKAV KVVSEVFDPE GPTCLETRLQ LYKEGLQGSL TSLKNPLTMM ANHYKQHCPP TPESPCATQN INFKSFKENL KDFLFNIPFD CWKPVKK (127)
• Applications: The GM-CSF protein can be used in cell culture, as a GM-CSF ELISA Standard, and as a Western Blot Control.
• Storage: -20 C