Active Recombinant Canine PDCD1 Protein, Fc-tagged, Alexa Fluor 555 conjugated

Cat.No. : PDCD1-1057CAF555
Product Overview : Alexa Fluor 555 conjugated recombinant canine PDCD1 (XP_543338.3) (Met1-Leu169) was expressed with the Fc region of human IgG1 at the C-terminus.
Availability December 09, 2024
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Source : HEK293
Species : Dog
Tag : Fc
Form : Lyophilized
Bio-activity : Measured by its binding ability in a functional ELISA. Immobilized canine PDCD1-Fc at 10 μg/mL (100 μL/well) can bind biotinylated canine PDCD1-Fc, The EC50 of biotinylated canine PDCD1-Fc is 0.16-0.4 μg/mL.
Molecular Mass : 43 kDa
Protein length : 383
N-terminal Sequence Analysis : Leu 25
Endotoxin : < 1.0 EU/ μg of the protein as determined by the LAL method.
Purity : > (20.2+76.0) % as determined by SDS-PAGE
Characteristic : Disulfide-linked homodimer
Labeled with Alexa Fluor 555 via amines
With an excitation and emission maximum of 555/565 nm, Alexa Fluor 555 can be efficiently excited using a 543 nm He-Ne laser line and detected under standard TRITC/Cy3 filters.
Stability : Samples are stable for up to 12 months from date of receipt at -70 centigrade.
Storage : Store it under sterile conditions at -20 to-70 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Storage Buffer : Lyophilized from sterile PBS, pH 7.4, 5%-8% trehalose and mannitol.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 μg/μL. Centrifuge the vial at 4 centigrade before opening to recover the entire contents.
Gene Name : PDCD1 programmed cell death 1 [ Canis lupus familiaris ]
Official Symbol : PDCD1
Synonyms : PD-1; programmed death 1
Gene ID : 486213
mRNA Refseq : NM_001314097
Protein Refseq : NP_001301026

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
06/06/2021

    Timely antibody validation, a valuable asset for our laboratory.

    02/12/2021

      Precise protein quantification, fundamental for maintaining data accuracy.

      06/20/2019

        Dependable peptide synthesis, accelerates our peptide-based projects effectively.

        Q&As (14)

        Ask a question
        What are the mechanisms by which PDCD1 modulates the immune response to viral infections? 07/31/2022

        PDCD1 modulates responses to viral infections, affecting T cell function and viral clearance.

        What are the mechanisms by which PDCD1 modulates the immune response to viral infections? 11/09/2021

        PDCD1 modulates responses to viral infections, affecting T cell function and viral clearance.

        What role does PDCD1 play in the development of immune tolerance? 10/15/2021

        PDCD1 helps develop immune tolerance, preventing overactive immune responses.

        How does PDCD1 influence the balance between immune activation and autoimmunity? 05/23/2021

        PDCD1 maintains a balance between immune response and autoimmunity, preventing self-reactivity.

        How does PDCD1 contribute to the exhaustion of T cells in chronic infections and cancer? 08/13/2020

        PDCD1 contributes to T cell exhaustion in chronic diseases and cancers, reducing immune efficacy.

        How does PDCD1 influence the balance between immune activation and autoimmunity? 08/05/2020

        PDCD1 maintains a balance between immune response and autoimmunity, preventing self-reactivity.

        What is the impact of PDCD1 on the effectiveness of immunotherapy in treating cancers? 12/05/2019

        PDCD1's role in immunotherapy is pivotal, as blocking PD-1 enhances anti-tumor responses.

        How does PDCD1 contribute to the exhaustion of T cells in chronic infections and cancer? 11/21/2019

        PDCD1 contributes to T cell exhaustion in chronic diseases and cancers, reducing immune efficacy.

        How does PDCD1 (PD-1) regulate immune checkpoint pathways in T cells? 04/24/2019

        PDCD1 regulates T cell activity by inhibiting immune responses, crucial in immune checkpoints.

        What is the impact of PDCD1 on the effectiveness of immunotherapy in treating cancers? 01/19/2019

        PDCD1's role in immunotherapy is pivotal, as blocking PD-1 enhances anti-tumor responses.

        What role does PDCD1 play in the development of immune tolerance? 12/08/2018

        PDCD1 helps develop immune tolerance, preventing overactive immune responses.

        How do alterations in PDCD1 expression or signaling affect autoimmune disease progression? 06/24/2018

        Changes in PDCD1 signaling impact autoimmune disease progression, influencing immune system activity.

        How does PDCD1 (PD-1) regulate immune checkpoint pathways in T cells? 06/24/2018

        PDCD1 regulates T cell activity by inhibiting immune responses, crucial in immune checkpoints.

        How do alterations in PDCD1 expression or signaling affect autoimmune disease progression? 02/06/2018

        Changes in PDCD1 signaling impact autoimmune disease progression, influencing immune system activity.

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