Active Recombinant Cynomolgus IL2RA&IL2RB&IL2RG protein, Fc-Avi-tagged, Biotinylated

• Cat.No.: IL2RA&IL2RB&IL2RG-0200C
• Product Overview: Biotinylated Recombinant Cynomolgus IL2RA&IL2RB&IL2RG protein(Ala27-Thr240(IL-2RB)&Glu22-Glu238(IL-2RA)&Leu23-Pro255(IL-2RG)), fused with Fc and Avi tag, was expressed in HEK293.

Specification

• Source: HEK293
• Species: Cynomolgus
• Tag: Fc-Avi
• Form: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
• Bio-activity: Immobilized Human IL-2, His Tag at 5 μg/mL (100 μL/well) can bind Biotinylated Cynomolgus IL-2RB&IL-2RA&IL-2RG, Fc,Avitag&Fc,Avitag with a linear range of 8-125 ng/mL.
• Molecular Mass: The reducing (R) protein migrates as 65-70 kDa and 115-130 kDa respectively due to glycosylation.
• Proteinlength: Ala27-Thr240(IL-2RB)&Glu22-Glu238(IL-2RA)&Leu23-Pro255(IL-2RG)
• Endotoxin: Less than 1.0 EU per μg by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Storage: For long term, the product should be stored at lyophilized state at -20°C or lower.Please avoid repeated freeze-thaw cycles. This product is stable after at:
  -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
• Official Symbol: IL2RA

Gene Information

• Official Symbol: IL2RA

Reviews

09/29/2022

Security is very high and can be used with confidence.

06/05/2021

Structure is very stable and not prone to mutation.

03/14/2019

The amount of expression is very high and can be easily detected.

Q&As

Is there any adverse effect of IL2RA combined with other drugs?

The combination of IL2RA and other drugs may produce nausea, vomiting, rash and other adverse reactions, should be monitored.

How often is IL2RA used?

The frequency of use of IL2RA depends on the specific situation of the patient, and is generally used 1-3 times per week.

Whether there is an effect of IL2RA?

IL2RA, in the right dosage and frequency of use, can significantly relieve symptoms of diseases such as autoimmune diseases and organ transplant rejection.

Can IL2RA treat cancer?

Can assist in the treatment of some types of malignant tumors, but it is not a complete cure for cancer.

How effective is IL2RA treatment?

The effective rate of IL2RA therapy depends on many factors such as the type of disease, the patient's condition and the treatment regimen, and the effective rate is generally between 50% and 90%.

What are the indications for IL2RA?

Indications of IL2RA include a variety of autoimmune diseases, organ transplant rejection and malignant tumors.