Active Recombinant Full Length Human BLVRB Protein, His Tagged

• Cat.No.: BLVRB-08H
• Product Overview: Active Recombinant Full Length Human BLVRB Protein (Ala2-Gln206) with an N-terminal Met and 6-His tag was expressed in E.coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 2-206 aa
• Description: Enables biliverdin reductase [NAD(P)+] activity; peptidyl-cysteine S-nitrosylase activity; and riboflavin reductase (NADPH) activity. Involved in heme catabolic process; megakaryocyte differentiation; and negative regulation of insulin receptor signaling pathway. Located in cytosol; nucleoplasm; and plasma membrane. Is active in cytoplasm.
• Form: Supplied as a 0.2 μm filtered solution in Tris, NaCl, Brij and Glycerol.
• Bio-activity: Measured by the reduction of riboflavin 5'-monophosphate (FMN) using NADPH as the cofactor. The specific activity is >225 pmol/min/μg, as measured under the described conditions.
• Molecular Mass: 23 kDa
• Endotoxin: <1.0 EU/μg of the protein by the LAL method.
• Purity: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining.
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 centigrade as supplied. 3 months, -20 to -70 centigrade under sterile conditions after opening.
• Shipping: The product is shipped with polar packs.

Gene Information

• Gene Name: BLVRB biliverdin reductase B [ Homo sapiens (human) ]
• Official Symbol: BLVRB
• Synonyms: BLVRB; biliverdin reductase B; FLR; BVRB; SDR43U1; HEL-S-10; flavin reductase (NADPH); BVR-B; FR; GHBP; NADPH-dependent diaphorase; NADPH-flavin reductase; S-nitroso-CoA-assisted nitrosyltransferase; SNO-CoA-assisted nitrosyltransferase; biliverdin-IX beta-reductase; epididymis secretory protein Li 10; green heme-binding protein; short chain dehydrogenase/reductase family 43U, member 1; EC 1.5.1.30
• Gene ID: 645
• mRNA Refseq: NM_000713
• Protein Refseq: NP_000704
• MIM: 600941
• UniProt ID: P30043