| Description : |
The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene. |
| Source : |
Mammalian cells |
| Species : |
Human |
| Tag : |
Flag |
| Form : |
25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
| Bio-activity : |
Binding assay |
| Molecular Mass : |
86.4 kDa |
| AA Sequence : |
MSWSPSLTTQTCGAWEMKERLGTGG FGNVIRWHNQETGEQIAIKQCRQEL SPRNRERWCLEIQIMRRLTH PNVVAARDVPEGMQNLAPNDLPLLA MEYCQGGDLRKYLNQFENCCGLREG AILTLLSDIASALRYLHENR IIHRDLKPENIVLQQGEQRLIHKII DLGYAKELDQGSLCTSFVGTLQYLA PELLEQQKYTVTVDYWSFGT LAFECITGFRPFLPNWQPVQWHSKV RQKSEVDIVVSEDLNGTVKFSSSLP YPNNLNSVLAERLEKWLQLM LMWHPRQRGTDPTYGPNGCFKALDD ILNLKLVHILNMVTGTIHTYPVTED ESLQSLKARIQQDTGIPEED QELLQEAGLALIPDKPATQCISDGK LNEGHTLDMDLVFLFDNSKITYETQ ISPRPQPESVSCILQEPKRN LAFFQLRKVWGQVWHSIQTLKEDCN RLQQGQRAAMMNLLRNNSCLSKMKN SMASMSQQLKAKLDFFKTSI QIDLEKYSEQTEFGITSDKLLLAWR EMEQAVELCGRENEVKLLVERMMAL QTDIVDLQRSPMGRKQGGTL DDLEEQARELYRRLREKPRDQRTEG DSQEMVRLLLQAIQSFEKKVRVIYT QLSKTVVCKQKALELLPKVE EVVSLMNEDEKTVVRLQEKRQKELW NLLKIACSKVRGPVSGSPDSMNASR LSQPGQLMSQPSTASNSLPE
PAKKSEELVAEAHNLCTLLENAIQD TVREQDQSFTALDWSWLQTEEEEHS CLEQASTRTRPLEQKLISEEDLAAN DILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining. |
| Stability : |
Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Storage : |
Store at -80 centigrade. |
| Concentration : |
>50 ug/mL as determined by microplate BCA method. |
| Preparation : |
Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Protein Families : |
Druggable Genome, Protein Kinase, Transcription Factors |
| Protein Pathways : |
Acute myeloid leukemia, Adipocytokine signaling pathway, Apoptosis, B cell receptor signaling pathway, Chemokine signaling pathway, Chronic myeloid leukemia, Cytosolic DNA-sensing pathway, Epithelial cell signaling in Helicobacter pylori infection, Insulin signaling pathway, MAPK signaling pathway, Neurotrophin signaling pathway, NOD-like receptor signaling pathway, Pancreatic cancer, Pathways in cancer, Prostate cancer, RIG-I-like receptor signaling pathway, Small cell lung cancer, T cell receptor signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus |
