Active Recombinant Full Length Human MAVS Protein, C-Flag-tagged

• Cat.No.: MAVS-149HFL
• Product Overview: Recombinant Full Length Human MAVS Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral innate immunity.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Bio-activity: Surface Plasmon Ressonance (SPR)
• Molecular Mass: 56.3 kDa
• AA Sequence: MPFAEDKTYKYICRNFSNFCNVDVV EILPYLPCLTARDQDRLRATCTLSG NRDTLWHLFNTLQRRPGWVE YFIAALRGCELVDLADEVASVYESY QPRTSDRPPDPLEPPSLPAERPGPP TPAAAHSIPYNSCREKEPSY PMPVQETQAPESPGENSEQALQTLS PRAIPRNPDGGPLESSSDLAALSPL TSSGHQEKDTELGSTHTAGA TSSLTPSRGPVSPSVSFQPLARSTP RASRLPGPTGSVVSTGTSFSSSSPG LASAGAAEGKQGAESDQAEP IICSSGAEAPANSLPSKVPTTLMPV NTVALKVPANPASVSTVPSKLPTSS KPPGAVPSNALTNPAPSKLP INSTRAGMVPSKVPTSMVLTKVSAS TVPTDGSSRNEETPAAPTPAGATGG SSAWLDSSFENRGLGSELSK PGVLASQVDSPFSGCFEDLAISAST SLGMGPCHGPEENEYKSEGTFGIHV AENPSIQLLEGNPGPPADPD
  GGPRPQADRKFQEREVPCHRPSPGA LWLQVAVTGVLVVTLLVVLYRRRLH TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Transmembrane
• Protein Pathways: Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway

Gene Information

• Gene Name: MAVS mitochondrial antiviral signaling protein [ Homo sapiens (human) ]
• Official Symbol: MAVS
• Synonyms: IPS1; VISA; IPS-1; CARDIF
• Gene ID: 57506
• mRNA Refseq: NM_020746.5
• Protein Refseq: NP_065797.2
• MIM: 609676
• UniProt ID: Q7Z434