Active Recombinant Full Length Human OCRL Protein, C-Flag-tagged
Cat.No. : | OCRL-459HFL |
Product Overview : | Recombinant Full Length Human OCRL Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Bio-activity : | Enzyme activity |
Molecular Mass : | 104 kDa |
AA Sequence : | MEPPLPVGAQPLATVEGMEMKGPLR EPCALTLAQRNGQYELIIQLHEKEQ HVQDIIPINSHFRCVQEAEE TLLIDIASNSGCKIRVQGDWIRERR FEIPDEEHCLKFLSAVLAAQKAQSQ LLVPEQKDSSSWYQKLDTKD KPSVFSGLLGFEDNFSSMNLDKKIN SQNQPTGIHREPPPPPFSVNKMLPR EKEASNKEQPKVTNTMRKLF VPNTQSGQREGLIKHILAKREKEYV NIQTFRFFVGTWNVNGQSPDSGLEP WLNCDPNPPDIYCIGFQELD LSTEAFFYFESVKEQEWSMAVERGL HSKAKYKKVQLVRLVGMMLLIFARK DQCRYIRDIATETVGTGIMG KMGNKGGVAVRFVFHNTTFCIVNSH LAAHVEDFERRNQDYKDICARMSFV VPNQTLPQLNIMKHEVVIWL GDLNYRLCMPDANEVKSLINKKDLQ RLLKFDQLNIQRTQKKAFVDFNEGE IKFIPTYKYDSKTDRWDSSG KCRVPAWCDRILWRGTNVNQLNYRS HMELKTSDHKPVSALFHIGVKVVDE RRYRKVFEDSVRIMDRMEND FLPSLELSRREFVFENVKFRQLQKE KFQISNNGQVPCHFSFIPKLNDSQY CKPWLRAEPFEGYLEPNETV DISLDVYVSKDSVTILNSGEDKIED ILVLHLDRGKDYFLTISGNYLPSCF GTSLEALCRMKRPIREVPVT KLIDLEEDSFLEKEKSLLQMVPLDE GASERPLQVPKEIWLLVDHLFKYAC HQEDLFQTPGMQEELQQIID CLDTSIPETIPGSNHSVAEALLIFL EALPEPVICYELYQRCLDSAYDPRI CRQVISQLPRCHRNVFRYLM AFLRELLKFSEYNSVNANMIATLFT SLLLRPPPNLMARQTPSDRQRAIQF LLGFLLGSEEDTRTRPLEQKLISEE DLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome |
Protein Pathways : | Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system |
Gene Name : | OCRL OCRL inositol polyphosphate-5-phosphatase [ Homo sapiens (human) ] |
Official Symbol : | OCRL |
Synonyms : | LOCR; DENT2; NPHL2; OCRL1; Dent-2; INPP5F; OCRL-1 |
Gene ID : | 4952 |
mRNA Refseq : | NM_000276.4 |
Protein Refseq : | NP_000267.2 |
MIM : | 300535 |
UniProt ID : | Q01968 |
Products Types
◆ Recombinant Protein | ||
OCRL-6310M | Recombinant Mouse OCRL Protein, His (Fc)-Avi-tagged | +Inquiry |
OCRL-1572H | Recombinant Human OCRL Protein, His (Fc)-Avi-tagged | +Inquiry |
OCRL-2972R | Recombinant Rhesus Macaque OCRL Protein, His (Fc)-Avi-tagged | +Inquiry |
OCRL-4845Z | Recombinant Zebrafish OCRL | +Inquiry |
OCRL-3154R | Recombinant Rhesus monkey OCRL Protein, His-tagged | +Inquiry |
◆ Lysates | ||
OCRL-3601HCL | Recombinant Human OCRL 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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