Active Recombinant Full Length Human SAA2 Protein, C-Flag-tagged

• Cat.No.: SAA2-220HFL
• Product Overview: Recombinant Full Length Human SAA2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Finally, antimicrobial activity against S. aureus and E. coli resides in the N-terminal portion of the mature protein.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Bio-activity: Cell treatment
• Molecular Mass: 13.3 kDa
• AA Sequence: MKLLTGLVFCSLVLSVSSRSFFSFL GEAFDGARDMWRAYSDMREANYIGS DKYFHARGNYDAAKRGPGGAWAAEV ISNARENIQRLTGHGAEDSLADQAA NKWGRSGRDPNHFRPAGLPEKY TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome

Gene Information

• Gene Name: SAA2 serum amyloid A2 [ Homo sapiens (human) ]
• Official Symbol: SAA2
• Synonyms: SAA; SAA1
• Gene ID: 6289
• mRNA Refseq: NM_030754.5
• Protein Refseq: NP_110381.2
• MIM: 104751
• UniProt ID: P0DJI9