Active Recombinant Full Length Rat HDAC6 Protein, N-GST-tagged

• Cat.No.: HDAC6-36RFL
• Product Overview: Recombinant full-length rat HDAC6 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Description: Enables deacetylase activity. Involved in several processes, including generation of neurons; regulation of protein modification process; and response to glucocorticoid. Located in axon and centrosome. Used to study polycystic kidney disease and polycystic liver disease. Biomarker of hypertension and polycystic liver disease. Human ortholog(s) of this gene implicated in chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia. Orthologous to human HDAC6 (histone deacetylase 6).
• Source: Insect cells
• Species: Rat
• Tag: GST
• Form: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mMDTT, 25% glycerol.
• Bio-activity: 25,618 RLU/min/ng
• Molecular Mass: Observed MW ~159 kDa.
  Calculated MW ~157 kDa.
• Purity: >90%
• Stability: lyr at -70 centigrade from date of shipment.
• Storage: Store product at -70 centigrade.For optimal storage, aliquot target in to smaller quantities after centrifugation and store at recommended temperature. For most favorable performance,avoid repeated handling and multiplefreeze/thaw cycles.
• Concentration: 0.1 ug/ul

Gene Information

• Gene Name: Hdac6 histone deacetylase 6 [ Rattus norvegicus (Norway rat) ]
• Official Symbol: HDAC6
• Synonyms: HD6; JM21; KIAAO901
• Gene ID: 108348065
• mRNA Refseq: XM_039100468.1
• Protein Refseq: XP_038956396.1
• UniProt ID: A0A1L5YJQ7