Active Recombinant Human ANGPTL2 Protein, His tagged

Cat.No. : ANGPTL2-13H
Product Overview : Active Recombinant Human ANGPTL2 Protein (Thr260-His493) with a C-terminal 6-His tag was expressed in Chinese Hamster Ovary cell line.
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Species : Human
Source : CHO
Tag : His
Protein Length : 260-493 aa
Description : Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 protein is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action.
Bio-activity : Measured by its binding ability in a functional ELISA. When Recombinant Human Angiopoietin-like Protein 2/ANGPTL2 is immobilized at 1 μg/mL, 100 μL/well, the concentration of Recombinant Human LILRB2/CD85d/ILT4 Fc Chimera Recombinant Human ILT4/CD85d Fc Chimera that produces 50% of the optimal binding response is 6-48 ng/mL.
N-terminal Sequence Analysis : Thr260
Molecular Mass : 28 kDa
Endotoxin : < 0.1 EU/μg of the protein by the LAL method.
Purity : > 95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining.
Storage : Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Storage Buffer : Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution : Reconstitute at 500 μg/mL in PBS.
Shipping : The product is shipped at ambient temperature.
Reference : 1. Kim, I. et al. (1999) J Biol Chem 274:26523. 2. Santulli, G. et al. (2014) Front Endocrinol 5:4. 3. Tabata, M. et al. (2009) Cell Metab 10:178.
Gene Name ANGPTL2 angiopoietin-like 2 [ Homo sapiens (human) ]
Official Symbol ANGPTL2
Synonyms ANGPTL2; angiopoietin-like 2; angiopoietin-related protein 2; ARP2; HARP; angiopoietin-like protein 2; MGC8889
Gene ID 23452
mRNA Refseq NM_012098
Protein Refseq NP_036230
MIM 605001
UniProt ID Q9UKU9

Not For Human Consumption!

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