Active Recombinant Human BIRC2 protein, Avi-tagged

• Cat.No.: BIRC2-3104H
• Product Overview: Active Recombinant Human BIRC2 protein(Glu 144-Leu 356)(NP_001157.1) was expressed in E. coli, fused with the AVI tag at the C-terminus, and two additional amino acids (Gly & Pro) at the N-terminus.

Specification

• Species: Human
• Source: E. coli
• Tag: Avi
• Protein Length: 144-356 aa
• Form: Lyophilized from sterile 10mM Tris, 5% glycerol, 0.5mM EDTA, 5mM DTT, pH 7.5.
• Bio-activity: Measured by its ability to inhibit DEVD-AFC cleavage activity in cell extracts activated by addition of cytochrome c and dATP. The IC50 for this effect is typically 450-750 nM.
• Molecular Mass: The recombinant human cIAP1 consists of 230 amino acids and has a calculated molecular mass of 26.5 kDa as estimated by SDS-PAGE under reducing conditions.
• Purity: > 92 % as determined by SDS-PAGE
• Storage: Store it under sterile conditions at -20°C to -80°C upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
• protein Refseq-Weblink: http://www.ncbi.nlm.nih.gov/protein/NP_001157.1
• Unit ID: Q13490
• Unit ID-Weblink: https://www.uniprot.org/uniprotkb/Q13490

Gene Information

• Gene Name: BIRC2 baculoviral IAP repeat containing 2 [ Homo sapiens ]
• Official Symbol: BIRC2
• Synonyms: BIRC2; baculoviral IAP repeat containing 2; API1, baculoviral IAP repeat containing 2; baculoviral IAP repeat-containing protein 2; apoptosis inhibitor 1; c IAP1; cIAP1; hiap 2; MIHB; NFR2 TRAF signalling complex protein; RNF48; IAP-2; IAP homolog B; RING finger protein 48; inhibitor of apoptosis protein 2; baculoviral IAP repeat-containing 2; NFR2-TRAF signalling complex protein; TNFR2-TRAF-signaling complex protein 2; API1; HIAP2; Hiap-2; c-IAP1
• Gene ID: 329
• mRNA Refseq: NM_001166
• protein Refseq: NP_001157
• MIM: 601712