Recombinant Human BIRC2 protein, His & S-tagged

• Cat.No.: BIRC2-1168H
• Product Overview: Recombinant Human BIRC2 aa. (Asn148~Ser298 fused with N-terminal His & S tag was produced in E. coli cells.

Specification

• Description: The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: His & S
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 22.8kDa.
• Protein length: Asn148~Ser298
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 6.0.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: BIRC2 baculoviral IAP repeat containing 2 [ Homo sapiens (human) ]
• Official Symbol: BIRC2
• Synonyms: BIRC2; baculoviral IAP repeat containing 2; API1; MIHB; HIAP2; RNF48; cIAP1; Hiap-2; c-IAP1; baculoviral IAP repeat-containing protein 2; IAP homolog B; IAP-2; NFR2-TRAF signalling complex protein; RING finger protein 48; RING-type E3 ubiquitin transferase BIRC2; TNFR2-TRAF-signaling complex protein 2; apoptosis inhibitor 1; cellular inhibitor of apoptosis 1; inhibitor of apoptosis protein 2
• Gene ID: 329
• mRNA Refseq: NM_001166.4
• Protein Refseq: NP_001157.1
• UniProt ID: Q13490