Active Recombinant Human Basic Fibroblast Growth Factor
| Cat.No. : | FGF2-5H |
| Product Overview : | Human basic FGF is produced by genetically engineered yeast, and purified by heparin-Sepharose affinity chromatography. |
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| Description : | Human Basic Fibroblast Growth Factor is a mitogen that stimulates cell growth for such cells as fibroblasts, endothelial cells, myoblasts, glial cells and smooth muscle cells. Basic FGF is composed of 146 amino acid residues (pro 1 to ser 146), and is 55% homologous with acidic FGF, including two conserved cysteine residues. |
| Source : | yeast |
| Species : | Human |
| Form : | Lyophilized powder |
| Bio-activity : | The mitogenic activity of human basic FGF is identical to natural bovine basic FGF, as measured by stimulation of 3H-thymidine incorporation into human foreskin fibroblast cells. |
| Molecular Mass : | 17.5 KDa |
| Purity : | Over 95% pure by N-terminal amino acid sequencing, amino acid composition, HPLC analysis, and SDS gel electrophoresis. |
| Stability : | Several months, lyophilized or in solution, at pH 6-7 and +4°C. |
| Storage : | Store at +4°C. Reconstitution is best in water or buffer near neutral pH, since it is unstable in acidic solutions. After reconstitution, storage in aliquots at -80°C is recommended. |
| Tag : | Non |
| Gene Name : | FGF2 fibroblast growth factor 2 (basic) [ Homo sapiens (human) ] |
| Official Symbol : | FGF2 |
| Synonyms : | FGF2; fibroblast growth factor 2 (basic); BFGF; FGFB; HBGF-2; fibroblast growth factor 2; prostatropin; heparin-binding growth factor 2; basic fibroblast growth factor Bfgf; Basic fibroblast growth factor |
| Gene ID : | 2247 |
| mRNA Refseq : | NM_002006 |
| Protein Refseq : | NP_001997 |
| MIM : | 134920 |
| UniProt ID : | P09038 |
| Chromosome Location : | 4q26 |
| Pathway : | Activated point mutants of FGFR2; Adaptive Immune System; Angiopoietin receptor Tie2-mediated signaling |
| Function : | chemoattractant activity; cytokine activity; fibroblast growth factor receptor binding |
Products Types
| ◆ Recombinant Protein | ||
| FGF2-1487H | Recombinant Human FGF2 Protein, His-tagged | +Inquiry |
| FGF2-06B | Recombinant Bovine/Porcine FGF2 Protein | +Inquiry |
| FGF2-2185C | Recombinant Cattle FGF2 Protein, His-tagged | +Inquiry |
| FGF2-78P | Recombinant Active Pig FGF2 Protein, His-tagged(N-ter) | +Inquiry |
| FGF2-1988R | Recombinant Rat FGF2 Protein, His (Fc)-Avi-tagged | +Inquiry |
| ◆ Native Protein | ||
| FGF2-34B | Active Native Bovine bFGF | +Inquiry |
| FGF2-26551TH | Native Human FGF2 | +Inquiry |
| ◆ Lysates | ||
| FGF2-638HCL | Recombinant Human FGF2 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (2)
Write a reviewThe technical expert communicated with me in time to understand the progress of my experiment and gave me suggestions for improvement.
The purchased protein is suitable for WB experiments and I am satisfied with the results.
Q&As (6)
Ask a questionFGF2 promotes cell migration and angiogenesis and regulates bone homeostatic balance.
FGF2 is widely expressed in the nervous system.
FGF2 is mainly expressed in tissues such as mammary glands and ovaries of sheep.
FGF1 has a high degree of homology with FGF2.
FGF2 is involved in diseases such as cardiovascular disease, breast disease and bone homeostasis.
FGF2 negatively regulates bone homeostasis.
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