- Human(12)
Active Recombinant Human BIRC3 Protein, GST-tagged, Active
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Cat.No. : | BIRC3-635H Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant Human BIRC3 fused with GST tag at N-terminal was expressed in Insect cells. |
Description : | BIRC3 or baculoviral IAP repeat containing 3 is a member of the IAP family of proteins. BIRC3 inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and thereby interfering with activation of ICE-like proteases. BIRC3 inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. BIRC3 is a potential oncogene which is overexpressed in multiple lung cancers with or without higher copy numbers. BIRC3 is a key regulator of NOD innate immunity signaling. |
Source : | Insect cells |
Species : | Human |
Tag : | GST |
Form : | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol |
Bio-activity : | 17 nmol/min/mg |
Molecular Mass : | 105 kDa |
Purity : | >75% |
Applications : | Ubiquitin Enzyme Assay, Western Blot |
Stability : | 1 year at - 70 centigrade from the date of shipment. |
Storage : | Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1 ug/ml |
Figure : |
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Gene Name : | BIRC3 baculoviral IAP repeat containing 3 [ Homo sapiens ] |
Official Symbol : | BIRC3 |
Synonyms : | BIRC3; baculoviral IAP repeat containing 3; API2, baculoviral IAP repeat containing 3; baculoviral IAP repeat-containing protein 3; apoptosis inhibitor 2; c IAP2; cIAP2; hiap 1; inhibitor of apoptosis protein 1; MALT2; mammalian IAP homolog C; MIHC; RNF49; TNFR2 TRAF signaling complex protein; IAP-1; IAP homolog C; RING finger protein 49; baculoviral IAP repeat-containing 3; TNFR2-TRAF signaling complex protein; TNFR2-TRAF-signaling complex protein 1; AIP1; API2; CIAP2; HAIP1; HIAP1; c-IAP2; |
Gene ID : | 330 |
mRNA Refseq : | NM_001165 |
Protein Refseq : | NP_001156 |
MIM : | 601721 |
UniProt ID : | Q13489 |
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◆ Lysates
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