Active Recombinant Human BMP7 Protein, Animal Free

• Cat.No.: BMP7-05H
• Product Overview: Recombinant Human BMP7 Protein without tag was expressed in Human cells.
  Animal Free and Xeno Free

Specification

• Species: Human
• Source: Human Cells
• Description: Bone morphogenetic protein 7 (BMP-7), also known as osteogenic protein 1 (OP1) is a member of transforming growth factor β family that includes more than 20 structurally related bone growth factors. BMP-7 plays an important role in cartilage and bone formation. It also plays a role in calcium regulation and kidney development. Mature human BMP-7 is usually a homodimer consisting of two antiparallel monomers of 139 amino acids. Dimerization is facilitated by a disulfide bridge formed between the monomer, which contains three intrachain disulfide bridges arranged in a cysteine knot motif.
• Bio-activity: The activity was measured by its ability to induce alkaline phosphatase production in the ATDC-5 cell line (Mouse chondrogenic cell line).
• Molecular Mass: 30-38 kDa
• Endotoxin: <0.5 EU/ μg
• Purity: High Purity, >95% by SDS-PAGE
• Stability: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -80 centigrade under sterile conditions after reconstitution.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution in PBS without carrier protein
• Reconstitution: Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 4 mM HCl containing at least 0.1% human or bovine serum albumin.

Gene Information

• Gene Name: BMP7 bone morphogenetic protein 7 [ Homo sapiens (human) ]
• Official Symbol: BMP7
• Synonyms: BMP7; bone morphogenetic protein 7; OP 1; osteogenic protein 1; BMP-7; OP-1
• Gene ID: 655
• mRNA Refseq: NM_001719
• Protein Refseq: NP_001710
• MIM: 112267
• UniProt ID: P18075