Active Recombinant Human CD19 Protein, Fc-tagged, Alexa Fluor 647 conjugated
Cat.No. : | CD19-3307HAF647 |
Product Overview : | Alexa Fluor 647 conjugated recombinant human CD19(Pro 20 - Pro 278) fused with with a human IgG1 with a human IgG1 Fc tag tag at C-terminal was expressed in HEK293. |
Unit | |
Price | |
Qty |
- Specification
- Gene Information
- Related Products
Source : | HEK293 |
Species : | Human |
Tag : | Fc |
Form : | Lyophilized |
Bio-activity : | Measured by its binding ability in a functional ELISA. Immobilized Mouse anti-human CD19 Mab FMC63 or HIB19 10 μg/mL (100 μL/well) can bind Human CD19, Fc Tag with a linear ranger of 10-1000 ng/mL. Measured by its binding ability in a functional ELISA. Immobilized Human CD9, His Tag at 2 μg/mL (100 μL/well) can bind Human CD19, Fc Tag with a linear range of 0.05-0.5 μg/mL. |
Molecular Mass : | Has a calculated MW of 55.1 kDa. DTT-reduced Protein migrates as 62-70 kDa in SDS-PAGE due to glycosylation. |
Protein length : | Pro20-Pro278 |
N-terminal Sequence Analysis : | Pro 20 |
Endotoxin : | < 1.0 EU/ μg of the Human CD19 (20-278), Fc Tag by the LAL method. |
Purity : | > 95 % as determined by SDS-PAGE |
Characteristic : | Disulfide-linked homodimer Labeled with Alexa Fluor 647 via amines Excitation = 650 nm Emission = 668 nm |
Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4 centigrade); After reconstitution under sterile conditions for 3 months (-70 centigrade). |
Storage Buffer : | Lyophilized from 0.22 μm filtered solution in 50 mM tris, 100 mM glycine, pH7.5. Normally Mannitol or Trehalose are added as protectants before lyophilization. |
Gene Name : | CD19 CD19 molecule [ Homo sapiens ] |
Official Symbol : | CD19 |
Synonyms : | CD19; CD19 molecule; CD19 antigen; B-lymphocyte antigen CD19; differentiation antigen CD19; T-cell surface antigen Leu-12; B-lymphocyte surface antigen B4; B4; CVID3; MGC12802; |
Gene ID : | 930 |
mRNA Refseq : | NM_001178098 |
Protein Refseq : | NP_001171569 |
MIM : | 107265 |
UniProt ID : | P15391 |
Products Types
◆ Recombinant Protein | ||
Cd19-828M | Recombinant Mouse Cd19 Protein, MYC/DDK-tagged | +Inquiry |
CD19-130H | Recombinant Human CD19 Protein, Fc-tagged | +Inquiry |
CD19-0732H | Recombinant Human CD19 Protein, GST-Tagged | +Inquiry |
CD19-26H | Recombinant Human CD19 Protein (20-291), C-His-tagged | +Inquiry |
CD19-128H | Recombinant Human CD19 Protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
CD19-2164MCL | Recombinant Mouse CD19 cell lysate | +Inquiry |
CD19-2005HCL | Recombinant Human CD19 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionCAR-T cells are engineered to express a receptor that recognizes CD19 on the surface of cancerous B cells. When they encounter these cells, they destroy them.
CD19 deficiencies can lead to primary immunodeficiencies, making individuals more susceptible to infections.
Side effects may include cytokine release syndrome (CRS), neurologic toxicity, and long-term B-cell aplasia.
CAR-T cell therapy is used to treat B-cell malignancies such as acute lymphoblastic leukemia (ALL) and certain types of non-Hodgkin lymphoma.
CAR-T cell therapy has shown remarkable effectiveness in inducing remissions in patients with CD19-positive malignancies, particularly in those who have relapsed or failed conventional treatments.
Customer Reviews (3)
Write a reviewThe manufacturer of CD19 protein has consistently provided outstanding technical support that has surpassed my expectations.
This protein demonstrates remarkable purity, stability, and specificity, ensuring utmost accuracy and reproducibility in my research endeavors.
Their dedication to customer satisfaction has been instrumental in overcoming obstacles and achieving successful results in my experiments.
Ask a Question for All CD19 Products
Required fields are marked with *
My Review for All CD19 Products
Required fields are marked with *
Inquiry Basket