Active Recombinant Human CD40, Fc-tagged, Biotinylated
Cat.No. : | CD40-577H |
Product Overview : | The recombinant human CD40-Fc fusion is expressed as a 401 amino acid protein consisting of Glu21 - Arg193 region of CD40 (UniProt accession #P25942) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions. |
- Specification
- Gene Information
- Related Products
Source : | Human cells |
Species : | Human |
Tag : | Fc |
Form : | Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule). |
Bio-activity : | Binds to its ligand CD40L/CD154 and inhibits CD40L--induced signaling activity including NF-κB activation and proliferation of human B cells. |
Molecular Mass : | Calculated molecular mass (kDa): 44.7; Estimated by SDS-PAGE under reducing condition (kDa): 55-60 |
Endotoxin : | <0.1 eu per 1 μg of purified recombinant protein determined by the |
Purity : | >95% judged by SDS-PAGE under reducing condition |
Storage : | The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles. |
Gene Name : | CD40 CD40 molecule, TNF receptor superfamily member 5 [ Homo sapiens ] |
Official Symbol : | CD40 |
Synonyms : | CD40; CD40 molecule, TNF receptor superfamily member 5; TNFRSF5, tumor necrosis factor receptor superfamily, member 5; tumor necrosis factor receptor superfamily member 5; Bp50; p50; CD40L receptor; CD40 type II isoform; B cell-associated molecule; B cell surface antigen CD40; B-cell surface antigen CD40; CD40 antigen (TNF receptor superfamily member 5); tumor necrosis factor receptor superfamily, member 5; nerve growth factor receptor-related B-lymphocyte activation molecule; CDW40; TNFRSF5; MGC9013; |
Gene ID : | 958 |
mRNA Refseq : | NM_001250 |
Protein Refseq : | NP_001241 |
MIM : | 109535 |
UniProt ID : | P25942 |
Chromosome Location : | 20q12-q13.2 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Asthma, organism-specific biosystem; Asthma, conserved biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; |
Function : | enzyme binding; protein binding; receptor activity; signal transducer activity; |
Products Types
◆ Recombinant Protein | ||
CD40-627C | Recombinant Cynomolgus monkey CD40 Protein, Fc-tagged | +Inquiry |
CD40-3225M | Recombinant Mouse CD40 protein(Met1-Arg193), rFc-tagged | +Inquiry |
CD40-628H | Recombinant Human CD40 Protein | +Inquiry |
CD40-631M | Recombinant Mouse CD40 Protein, Fc-tagged | +Inquiry |
CD40-928C | Recombinant Canine CD40 Protein (Glu21-Ala194), His-tagged | +Inquiry |
◆ Lysates | ||
CD40-1831MCL | Recombinant Mouse CD40 cell lysate | +Inquiry |
CD40-001CCL | Recombinant Canine CD40 cell lysate | +Inquiry |
CD40-2617HCL | Recombinant Human CD40 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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