CD40

  • Official Full Name

    CD40 antigen

  • Overview

    CD40 is a cell surface receptor that is expressed on the surface of all mature B cells, most mature B -cell malignancies, and some early B-cell acute lymphocytic leukemias, but is not expressed on plasma cells. The CD40 gene is localized to the long arm of chromosome 20, bands q12-q13.2. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation.
  • Synonyms

    CD40; CD40 molecule, TNF receptor superfamily member 5; p50; Bp50; CDW40; TNFRSF5; tumor necrosis factor receptor superfamily member 5; CD40L receptor; CD40 type II isoform; B cell-associated molecule; B cell surface antigen CD40; B-cell surface antigen CD40; CD40 antigen (TNF receptor superfamily member 5); tumor necrosis factor receptor superfamily, member 5; nerve growth factor receptor-related B-lymphocyte activation molecule; CD_antigen=CD40; CD40 antigen; Dacetuzumab; 880486-59-9; Teneliximab; 299423-37-3;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Antibody
  • GMP Proteins
  • Protein Pre-coupled Magnetic Beads
  • Canine
  • Chicken
  • Cynomolgus
  • Cynomolgus monkey
  • Cynomolgus Monkey
  • Dog
  • Homo sapiens (Human)
  • Human
  • Monkey
  • Mouse
  • Mus musculus (Mouse)
  • Rabbit
  • Rat
  • Rhesus
  • Rhesus macaque
  • Rhesus Macaque
  • Zebrafish
  • CHO
  • CHO cells
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293F
  • Human
  • Human Cell
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian cell
  • Mammalian Cell
  • Mammalian cells
  • Mouse
  • Rabbit
  • Wheat Germ
  • Yeast
  • Avi|Fc
  • C
  • His
  • rFc
  • Fc
  • Avi
  • Fc|His
  • His(C
  • ter)
  • GST
  • hFc
  • hIgG
  • His (Fc)
  • His|Fc
  • His|Fc|Avi
  • His|Flag|StrepII
  • His|T7
  • HlgG1 Fc
  • human|IgG1|Fc
  • LEVLFQ
  • Mouse|IgG2a|Fc
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CD40-493H Active Recombinant Human CD40, Fc Chimera HEK293 Fc
Human CD40-106H Active Recombinant Human CD40, HIgG1 Fc-tagged CHO Fc
Human CD40-108H Active Recombinant Human CD40 Protein, Fc-tagged CHO Fc
Human CD40-202H Active Recombinant Human CD40 protein, His/Fc-tagged, Biotinylated HEK293 His/Fc
Human CD40-105H Active Recombinant Human CD40, MIgG2a Fc-tagged CHO Fc
Human CD40-577H Active Recombinant Human CD40, Fc-tagged, Biotinylated Human Cell Fc
Human CD40-107H Active Recombinant Human CD40 Protein, His-tagged CHO His
Human CD40-369H Active Recombinant Human CD40 protein, Hi & Fc & Avi-tagged, Biotinylated HEK293 His/Fc/Avi Glu 21 - Arg 193
Human CD40-051H Active Recombinant Human CD40 protein, Fc/Avi-tagged, Biotinylated CHO cells Fc/Avi Glu21-Arg193
Human CD40-837H Active Recombinant Human CD40 protein, hFc-tagged Mammalian cell hFc 21-193aa
Human CD40-108HF Active Recombinant Human CD40 Protein, Fc-tagged, FITC conjugated CHO Fc 405
Human CD40-108HAF647 Active Recombinant Human CD40 Protein, Fc-tagged, Alexa Fluor 647 conjugated CHO Fc 405
Human CD40-108HAF488 Active Recombinant Human CD40 Protein, Fc-tagged, Alexa Fluor 488 conjugated CHO Fc 405
Human CD40-108HAF555 Active Recombinant Human CD40 Protein, Fc-tagged, Alexa Fluor 555 conjugated CHO Fc 405
Human CD40-174H Recombinant Human CD40, Fc-His tagged Human Cell Fc/His
Human CD40-2221H Active Recombinant Human CD40 protein, His-tagged HEK293 His Met1-Arg193
Human CD40-4980H Recombinant Human CD40 Molecule, TNF Receptor Superfamily Member 5 Human N/A
Human CD40-5119H Recombinant Human CD40, His-tagged E.coli His
Human CD40-27810TH Recombinant Human CD40, Fc-tagged Fc
Human CD40-0810H Recombinant Human CD40 Protein Wheat Germ N/A
Human CD40-518H Recombinant Human CD40 molecule, TNF receptor superfamily member 5, His-tagged E.coli His
Human CD40-0811H Active Recombinant Human CD40 Protein, His-Flag-StrepII-Tagged Human Cell His/Flag/StrepII
Human CD40-2222H Active Recombinant Human CD40 Protein, His & Avi-tagged, Biotinylated HEK293 His & Avi Glu 21 - Arg 193
Human CD40-0812H Recombinant Human CD40 Protein, GST-Tagged Wheat Germ GST
Human CD40-017H Recombinant Human CD40 protein, Fc-tagged (HPLC-verified) HEK293 human/IgG1/Fc Glu21-Arg193
Human CD40-2617HCL Recombinant Human CD40 cell lysate Human Cell N/A
Human CD40-31H Recombinant Human CD40 Protein (ECD), Fc-His-tagged(C-ter) HEK293 Fc-His(C-ter) Glu21-Arg193
Human CD40-371H Active Recombinant Human CD40 Protein, Fc & Avi-tagged, Biotinylated HEK293 Avi/Fc Glu 21 - Arg 193
Human CD40-108HP Recombinant Human CD40 protein, Fc-tagged, R-PE labeled CHO Fc
Human CD40-108HA Recombinant Human CD40 protein, Fc-tagged, APC labeled CHO Fc
Human CD40-174HAF647 Recombinant Human CD40 Protein, Fc/His-tagged, Alexa Fluor 647 conjugated HEK293 Fc/His 421
Human DMAB6033MH Mouse Anti-Human CD40 Monoclonal Antibody Mouse N/A
Human CD40-389H Recombinant Human CD40 protein, Mouse IgG2a Fc-tagged, low endotoxin HEK293 Mouse/IgG2a/Fc 173
Human CD40-174HAF555 Recombinant Human CD40 Protein, Fc/His-tagged, Alexa Fluor 555 conjugated HEK293 Fc/His 421
Human CD40-1087H Recombinant Human CD40 Protein (Met1-Arg193), His-tagged, Biotinylated HEK293 His Met1-Arg193
Human CD40-2221HAF555 Recombinant Human CD40 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His Glu21-Arg193
Human CD40-107HG Active GMP Recombinant Human CD40 protein HEK293 DNA sequence encoding Human CD40(NCBI Reference Sequence: NP_001241.1) was expressed with His tag at the C-terminal.
Human CD40-2221HAF488 Recombinant Human CD40 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His Glu21-Arg193
Human CD40-07H Recombinant Human CD40 Protein, hIgG/His-tagged HEK293 hIgG/His
Human CD40-679H Recombinant Human CD40 Protein, His-tagged HEK293F N-His Cys26-Gly187
Human CD40-1485H Recombinant Human CD40 Protein (Met1-Arg193), C-His tagged Mammalian cells C-His Met1-Arg193
Human CD40-174HF Recombinant Human CD40 Protein, Fc/His-tagged, FITC conjugated HEK293 Fc/His 421
Human CD40-174HAF488 Recombinant Human CD40 Protein, Fc/His-tagged, Alexa Fluor 488 conjugated HEK293 Fc/His 421
Human CD40-628H Recombinant Human CD40 Protein HEK293 277
Human CAB11500RH Rabbit Anti-Human CD40 Molecule, TNF Receptor Superfamily Member 5 Monoclonal Antibody Rabbit N/A
Human CD40-2964HF Recombinant Full Length Human CD40 Protein, GST tagged E.coli GST
Human CD40-629H Recombinant Human CD40 Protein, Fc-tagged HEK293 Fc 277
Human CD40-32H Recombinant Human CD40 Protein (ECD), His-tagged(C-ter) HEK293 His(C-ter) Glu21-Arg193
Human CD40-2221HAF647 Recombinant Human CD40 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His Glu21-Arg193
Human CD40-195H Recombinant Human CD40 Protein, C-His-tagged E.coli C-His
Human CD40-2221HF Recombinant Human CD40 Protein, His-tagged, FITC conjugated HEK293 His Glu21-Arg193
Human CD40-3237HF Recombinant Full Length Human CD40 Protein, GST-tagged In Vitro Cell Free System 393 amino acids
Human CD40-1511H Recombinant Human CD40 Protein (Cys26-Gly187), N-His tagged E.coli N-His Cys26-Gly187
Human CD40-13HFL Recombinant Full Length Human CD40 Protein, N-GST-tagged Wheat Germ N-GST 1-277 aa
Mouse Cd40-86M Active Recombinant Mouse Cd40, His-tagged HEK293 His
Mouse Cd40-4981M Active Recombinant Mouse CD40 Antigen Mouse N/A
Mouse Cd40-1715M Recombinant Mouse CD40 Antigen, Fc-His Mammalian cells His
Mouse Cd40-6892M Recombinant Mouse Cd40, Fc-His tagged Human Cell Fc/His
Mouse Cd40-6717M Recombinant Mouse Cd40 protein, His & T7-tagged E.coli His/T7 Cys26~Arg193 (Accession # P27512)
Mouse Cd40-81M Recombinant Mouse Cd40 protein, His-tagged Insect Cell His
Mouse Cd40-87M Recombinant Mouse Cd40 protein, His-tagged HEK293 His 170
Mouse CD40-1831MCL Recombinant Mouse CD40 cell lysate Human Cell N/A
Mouse Cd40-6892MAF488 Recombinant Mouse Cd40 Protein, Fc/His-tagged, Alexa Fluor 488 conjugated HEK293 Fc/His 422
Mouse CD40-630M Recombinant Mouse CD40 Protein HEK293 289
Mouse Cd40-325MAF488 Recombinant Mouse CD40 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc Met1-Arg193, 405
Mouse CD40-1088M Recombinant Mouse CD40 Protein (Met1-Arg193), HlgG1 Fc-tagged HEK293 HlgG1 Fc Met1-Arg193
Mouse Cd40-1462M-B Recombinant Mouse Cd40 Protein Pre-coupled Magnetic Beads HEK293
Mouse CD40-2980M Active Recombinant Mouse CD40 protein, Fc-Avi-tagged, Biotinylated HEK293 Fc-Avi Val 24-Arg 193
Mouse Cd40-325M Active Recombinant Mouse Cd40 protein, Fc-tagged HEK293 Fc Val 24 - Arg 193
Mouse Cd40-325MF Recombinant Mouse CD40 Protein, Fc-tagged, FITC conjugated HEK293 Fc Met1-Arg193, 405
Mouse CD40-631M Recombinant Mouse CD40 Protein, Fc-tagged HEK293 Fc 289
Mouse Cd40-6892MF Recombinant Mouse Cd40 Protein, Fc/His-tagged, FITC conjugated HEK293 Fc/His 422
Mouse Cd40-325MAF647 Recombinant Mouse CD40 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc Met1-Arg193, 405
Mouse Cd40-6892MAF647 Recombinant Mouse Cd40 Protein, Fc/His-tagged, Alexa Fluor 647 conjugated HEK293 Fc/His 422
Mouse Cd40-325MAF555 Recombinant Mouse CD40 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc Met1-Arg193, 405
Mouse Cd40-6892MAF555 Recombinant Mouse Cd40 Protein, Fc/His-tagged, Alexa Fluor 555 conjugated HEK293 Fc/His 422
Mouse CD40-816M Recombinant Mouse CD40 Protein (Val24-Arg193), His-tagged Yeast His Val24-Arg193
Mouse CD40-3225M Recombinant Mouse CD40 protein(Met1-Arg193), rFc-tagged HEK293 C-rFc Met1-Arg193
Mouse Cd40-1462M Recombinant Mouse Cd40 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Cd40-8726R Recombinant Rat Cd40 protein, hFc-tagged HEK293 hFc Met1-Arg193
Rat Cd40-8727R Recombinant Rat Cd40 protein(Met1-Arg193), His-tagged HEK293 C-His Met1-Arg193
Rat Cd40-6718R Recombinant Rat Cd40 protein, His & T7-tagged E.coli His/T7 Val24~Arg193 (Accession # Q4QQW2)
Rat CD40-1262RCL Recombinant Rat CD40 cell lysate Human Cell N/A
Rat Cd40-8727RF Recombinant Rat Cd40 Protein, His-tagged, FITC conjugated HEK293 His 185
Rat Cd40-8727RAF647 Recombinant Rat Cd40 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His 185
Rat Cd40-8726RAF555 Recombinant Rat Cd40 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc 415
Rat Cd40-8726RAF488 Recombinant Rat Cd40 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc 415
Rat Cd40-8727RAF555 Recombinant Rat Cd40 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His 185
Rat Cd40-8727RAF488 Recombinant Rat Cd40 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His 185
Rat Cd40-8726RAF647 Recombinant Rat Cd40 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc 415
Rat Cd40-8726RF Recombinant Rat Cd40 Protein, Fc-tagged, FITC conjugated HEK293 Fc 415
Monkey CD40-8824CAF647 Recombinant Monkey CD40 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His Met1-Arg193, 184
Monkey CD40-8824CAF555 Recombinant Monkey CD40 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His Met1-Arg193, 184
Monkey CD40-8823CAF488 Recombinant Monkey CD40 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc 414
Monkey CD40-8824CF Recombinant Monkey CD40 Protein, His-tagged, FITC conjugated HEK293 His Met1-Arg193, 184
Monkey CD40-8823CF Recombinant Monkey CD40 Protein, Fc-tagged, FITC conjugated HEK293 Fc 414
Monkey CD40-8823CAF647 Recombinant Monkey CD40 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc 414
Monkey CD40-8824CAF488 Recombinant Monkey CD40 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His Met1-Arg193, 184
Monkey CD40-8823CAF555 Recombinant Monkey CD40 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc 414
Rabbit CD40-2151R Active Recombinant Rabbit CD40 protein, His-tagged HEK293 His Glu 77 - Arg 249
Dog CD40-153CAF555 Recombinant Canine CD40 Protein, LEVLFQ-tagged, Alexa Fluor 555 conjugated HEK293 LEVLFQ 181
Dog CD40-153CAF488 Recombinant Canine CD40 Protein, LEVLFQ-tagged, Alexa Fluor 488 conjugated HEK293 LEVLFQ 181
Dog CD40-167CAF555 Recombinant Canine CD40 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc 415
Dog CD40-165CAF555 Recombinant Canine CD40 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His Met1-Ala194, 185
Dog CD40-153CF Recombinant Canine CD40 Protein, LEVLFQ-tagged, FITC conjugated HEK293 LEVLFQ 181
Dog CD40-165CAF488 Recombinant Canine CD40 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His Met1-Ala194, 185
Dog CD40-167CF Recombinant Canine CD40 Protein, Fc-tagged, FITC conjugated HEK293 Fc 415
Dog CD40-165CF Recombinant Canine CD40 Protein, His-tagged, FITC conjugated HEK293 His Met1-Ala194, 185
Dog CD40-165CAF647 Recombinant Canine CD40 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His Met1-Ala194, 185
Dog CD40-153CAF647 Recombinant Canine CD40 Protein, LEVLFQ-tagged, Alexa Fluor 647 conjugated HEK293 LEVLFQ 181
Dog CD40-167CAF647 Recombinant Canine CD40 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc 415
Dog CD40-167CAF488 Recombinant Canine CD40 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc 415
Canine CD40-167C Recombinant Canine CD40, Fc tagged Human Cell Fc
Canine CD40-153C Recombinant Canine CD40, LEVLFQ tagged Human Cell Fc/His
Canine CD40-165C Recombinant Canine CD40, His-tagged Human Cell His Met1-Ala194
Canine CD40-001CCL Recombinant Canine CD40 cell lysate Human Cell N/A
Canine CD40-928C Recombinant Canine CD40 Protein (Glu21-Ala194), His-tagged Yeast His Glu21-Ala194
Cynomolgus CD40-85C Recombinant Cynomolgus CD40 protein, His-tagged HEK293 His 173
Cynomolgus CD40-23C Active Recombinant Cynomolgus CD40 protein, His-tagged HEK293 His Glu 21 - Arg 193
Cynomolgus Monkey CD40-8823C Recombinant Cynomolgus CD40, Fc tagged Human Cell Fc
Cynomolgus Monkey CD40-1254CCL Recombinant Cynomolgus CD40 cell lysate Human Cell N/A
Cynomolgus monkey CD40-627C Recombinant Cynomolgus monkey CD40 Protein, Fc-tagged HEK293 Fc 278
Cynomolgus monkey CD40-626C Recombinant Cynomolgus monkey CD40 Protein HEK293 278
Homo sapiens (Human) RFL32571HF Recombinant Full Length Human Tumor Necrosis Factor Receptor Superfamily Member 5(Cd40) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (21-277)
Mus musculus (Mouse) RFL13008MF Recombinant Full Length Mouse Tumor Necrosis Factor Receptor Superfamily Member 5(Cd40) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (20-289)
Rhesus CD40-8824C Recombinant Rhesus CD40 protein, His-tagged HEK293 His Met 1-Arg193
Rhesus macaque CD40-740R Active Recombinant Rhesus macaque CD40 protein, His-tagged HEK293 His Glu 21 - Arg 193
Rhesus macaque CD40-741R Recombinant Rhesus macaque CD40 protein, His-tagged HEK293 His 173
Rhesus macaque CD40-632R Recombinant Rhesus macaque CD40 Protein HEK293 278
Rhesus macaque CD40-633R Recombinant Rhesus macaque CD40 Protein, Fc-tagged HEK293 Fc 278
Rhesus macaque CD40-388R Recombinant Rhesus macaque CD40 protein, Fc-tagged HEK293 human/IgG1/Fc 173
Rhesus macaque CD40-2976R Active Recombinant Rhesus macaque CD40 protein, Fc-tagged HEK293 Fc Glu 21-Arg 193
Rhesus Macaque CD40-566R Recombinant Rhesus Macaque CD40 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CD40-566R-B Recombinant Rhesus Macaque CD40 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish CD40-7316Z Recombinant Zebrafish CD40 Mammalian Cell His
Chicken CD40-6231C Recombinant Chicken CD40 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CD40 Related Articles
  • CD40 Related Gene Family
  • CD40 Related Research Area
  • CD40 Related Signal Pathway

CD40 involved in several pathways and played different roles in them. We selected most pathways CD40 participated on our site, such as Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Cell adhesion molecules (CAMs), which may be useful for your reference. Also, other proteins which involved in the same pathway with CD40 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionIL18R1;OSM;LTB;CXCR4B;ACKR3B;Ccl21a;IRX1;Ifna11;IL12A
NF-kappa B signaling pathwayNFKB2;TICAM2;MYD88;ICAM1;VCAM1;MAP3K7;PLAU;BIRC2;LBP
Cell adhesion molecules (CAMs)PDCD1;CLDN17;JAM2A;TIGIT;CLDNC;CLDN7B;PTPRC;NCAM1;CLDNB
Toll-like receptor signaling pathwayIFNA7;CCL3;IKBKE;PIK3R3;CCL4;CXCL10;CCL4L2;IFNA6;MAPK12
Intestinal iICOS;CXCR4B;CD28;AICDA;MHC2DCB;CCL28;HLA-DPA1;H2-AA;BLB2
ne network for IgA productionCXCR4B;CCL28;BMA2;MHC2DEB;Icosl;HLA-DRB3;PIGR;CCL25B;Il2
MalariaGYPB;CCL2;IL6;CSF3;TGFB3;ITGAL;HBB;CD40LG;HBB-B2
ToxoplasmosisMAPK11;TAB2;IL10RB;CASP9;IL12A;HSPA6;Toxoplasma Gondii Dense Granule Protein 7;H2-AA;IRGM
HTLV-I infectionCDC26;PPP3R1;FZD3;FZD9;IL2RA;BUB1B;TNFRSF1A;MYBL2;CD3G
Epstein-Barr virus infectionPRKACB;HDAC4;NCOR2;MAPK13;HLA-A;CCNA2;SHFM1;POLR3GL;RBPJ
Transcriptional misregulation in cancerELK4;SPINT1;ATF1;BCL2L1;IL1R2;TAF15;ETV6;ETV4;MMP9
AsthmaHLA-DQA2;HLA-DQB1;TNF;HLA-DRB3;HLA-DMA;HLA-DRB1;IL3;FCER1A;IL13
AutoiFASLG;HLA-DQA2;HLA-DRB3;HLA-DQB1;HLA-DPA1;CD28;Fasl;HLA-DOB;CD86
ne thyroid diseaseHLA-G;IFNA8;CD40LG;H2-AA;CD80;CD86;IFNA5;Fasl;IL5
Systemic lupus erythematosusFCGR1A;SSB;HIST1H2AF;HLA-DOA;ELANE;HIST1H2AD;HLA-DRA;C9;SNRPB
Allograft rejectionHLA-DRB5;Il2;IL5;FAS;IL12A;HLA-DOB;Fasl;HLA-DQB1;GZMB
Primary iCD79A;IL7R;CD40LG;BLNK;ORAI1;PTPRC;TNFRSF13B;CD3D;TAP2
nodeficiencyCD8B;ZAP70;RFXANK;RFX5;CD8B1;IL2RG;TNFRSF13B;Cd79a, Cd79b;CD3E
Viral myocarditisHLA-C;HLA-DQA1;HLA-DQA2;H2-AA;ITGB2L;HLA-DMA;HLA-B;ABL2;HLA-DRB3

CD40 has several biochemical functions, for example, antigen binding, enzyme binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD40 itself. We selected most functions CD40 had, and list some proteins which have the same functions with CD40. You can find most of the proteins on our site.

Function Related Protein
antigen bindingHNRNPM;Ighg;LCK;KIR2DL3;IGHM;Ighg2b;IGLC2;LILRA1;IgG3
enzyme bindingTOP2B;CABYR;TSPAN33;DHCR24;CYB5A;HAND1;BCR;TSPYL1;CSF3
protein bindingRABIF;ENSA;RFPL3;RGL2;GPATCH8;NUDT16L1;ZFP64;CTDSP1;MYO5B
receptor activityNLGN4X;GRIN1B;CHRM3;ADIPOR1B;ABP1;NLGN2;VMN1R43;PVRL1A;VAC14
signal transducer activityIKBKG;MAPKAPK2;PPM1A;OPN4.1;TAS2R117;CXCR4B;OLFR502;PTH1RA;TAAR4
tumor necrosis factor-activated receptor activityCD27;TNFRSF10D;EDA2R;Tnfrsf26;RELT;FAS;NGFR;LTBR;TNFRSFA
ubiquitin protein ligase bindingHSPA5;BRCA1;JKAMP;AXIN1;SPG20;UBE2U;UBE2G1;UBE2G1B;ZFP746

CD40 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD40 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD40.

TRAF2; TRAF6; TRAF3; 21362046; SGK1; OGT; KATNA1; TXN; PCMT1; FBL; CALR

Chandraratne, S; von Bruehl, ML; et al. Critical Role of Platelet Glycoprotein Iba in Arterial Remodeling. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 35:589-597(2015).
Cozza, EM; Cooper, TK; et al. Protection from tumor recurrence following adoptive immunotherapy varies with host conditioning regimen despite initial regression of autochthonous murine brain tumors. CANCER IMMUNOLOGY IMMUNOTHERAPY 64:325-336(2015).
TNF
  • Q&As
  • Reviews

Q&As (5)

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Can CD40-targeted therapies be used in the treatment of infectious diseases? 05/31/2022

CD40 agonists have the potential to enhance immune responses against infectious agents, but their clinical use in this context is an area of ongoing research.

Are there any approved drugs targeting CD40 for clinical use? 05/07/2021

As of my knowledge cutoff date in January 2022, there were no FDA-approved drugs specifically targeting CD40. However, clinical trials were ongoing for CD40-targeted therapies.

Can CD40-targeted therapies be used in combination with other cancer treatments? 04/24/2019

Yes, CD40-targeted therapies are often investigated in combination with other treatments like checkpoint inhibitors or chemotherapy to enhance their effectiveness.

What are the potential side effects of CD40-targeted therapies in cancer treatment? 09/25/2018

Side effects may include flu-like symptoms, cytokine release syndrome, and immune-related adverse events, which can be managed with supportive care and close monitoring.

Are there ongoing clinical trials exploring CD40-targeted therapies for atherosclerosis? 04/25/2017

Research on CD40-targeted therapies for atherosclerosis is still in the experimental stages and not yet in advanced clinical trials.

Customer Reviews (3)

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Reviews
10/28/2021

    Its utilization in this technique has allowed for precise visualization and determination of protein structures with remarkable clarity and resolution.

    08/11/2021

      The reliable and high-quality results obtained using CD40 protein make it an excellent choice for researchers studying protein structures.

      10/07/2018

        CD40 protein has proved to be an invaluable tool in protein electron microscopy structure analysis.

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