Active Recombinant Human Choroideremia-like (Rab Escort Protein 2), His-tagged

• Cat.No.: CHML-1141H

Specification

• Species: Human
• Source: S.Cerevisiae
• Tag: His
• Description: REP-2 (Rab escort protein-2) binds to a wide range of RabGGTase with nanomolar affinities and supports the prenylation of RabGTPase mediated by RabGGTase, with an exception of Rab27.
• Purity: > 90% by SDS-PAGE.
• Form: Liquid. Supplied in 25 mM HEPES pH 7.2, 40 mM NaCl and 5 mM DTT.
• Activity: 1 pmol of REP-2 will mediate transfer of 2 pmol of geranylgeraniol by RabGGTase onto 1 pmol of Rab7 in 3 minutes.
• Storage: Quality guaranteed for 12 months. Store at -80°C.Avoid freeze / thaw cycles.
• Usage: For in vitro use only.

Gene Information

• Gene Name: CHML choroideremia-like (Rab escort protein 2) [ Homo sapiens ]
• Synonyms: choroideremia-like (Rab escort protein 2); REP2; FLJ10071; FLJ13361; CHML; choroideremia-like Rab escort protein 2; REP-2, Rab escort protein 2; REP-2 ; OTTHUMP00000037644; Choroideraemia-like protein; Rab escort protein 2
• Gene ID: 1122
• mRNA Refseq: NM_001821
• Protein Refseq: NP_001812
• MIM: 118825
• UniProt ID: P26374
• Chromosome Location: 1q42-qter
• Function: GTPase activator activity; Rab geranylgeranyltransferase activity